Evidence map›Paper›PMID 41290146›Full record

ArticleOpen biology2025

Initiators counteract Polycomb repression and stimulate long-range contacts between enhancers and the

Olga Kyrchanova, Ksenia Kudryashova, Vasilisa Dubrovskaya, Airat Ibragimov, Paul Schedl, Pavel Georgiev

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Olga KyrchanovaDepartment of the Control of Genetic Processes, Institute of Gene Biology Russian Academy of Sciences, 34/5 Vavilov St., Moscow 119334, Russia.ORCID 0000-0002-6249-0418
Ksenia KudryashovaDepartment of the Control of Genetic Processes, Institute of Gene Biology Russian Academy of Sciences, 34/5 Vavilov St., Moscow 119334, Russia.
Vasilisa DubrovskayaDepartment of the Control of Genetic Processes, Institute of Gene Biology Russian Academy of Sciences, 34/5 Vavilov St., Moscow 119334, Russia.ORCID 0009-0002-1742-0960
Airat IbragimovDepartment of the Control of Genetic Processes, Institute of Gene Biology Russian Academy of Sciences, 34/5 Vavilov St., Moscow 119334, Russia.
Paul SchedlPrinceton University, Princeton, NJ, USA.ORCID 0000-0001-5704-2349
Pavel GeorgievDepartment of the Control of Genetic Processes, Institute of Gene Biology Russian Academy of Sciences, 34/5 Vavilov St., Moscow 119334, Russia.ORCID 0000-0002-6509-3194

Funding

Russian Science Foundation
6 · The paper itself

Abstract

The specification of abdominal segments A5 to A9 depends on the expression of

Indexed as

DrosophilaDrosophila melanogasterDrosophila ProteinsEnhancer Elements, GeneticHomeodomain ProteinsPolycomb-Group ProteinsPromoter Regions, GeneticAnimalsBinding SitesGene Expression Regulation, DevelopmentalProtein BindingAbd-B proteins, DrosophilaDrosophila ProteinsHomeodomain ProteinsPolycomb-Group Proteinsbithoraxchromatin boundarychromatin insulatorenhancer–promoter interactionPolycombtethering element

Identifiers

PMID41290146
PMCPMC12646789

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.