ArticleNPJ microgravity2025
A combined individualized cycling exercise and artificial gravity training protocol as a spaceflight deconditioning countermeasure.
Article in NPJ microgravity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Artificial gravity during prolonged bed rest preserves resting metabolic rate but not muscle function: Evidence from the BRACE study.The Journal of physiology · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orthostatic intolerance (OI) remains a post-flight challenge for astronauts. As part of the ESA/CNES BRACE bed rest study, we tested, in ambulatory participants, a combined individualized cycling exercise and artificial gravity (AG) training procedure as a multi-system OI countermeasure. The training limits of cycling intensity and AG exposure were based on individual V̇O2peak and presyncopal AG level. In a randomized crossover design, heart rate (HR) and blood pressure responses were assessed during cycling with or without AG exposure. Our results demonstrated cardiovascular stimuli (i.e., higher HR and blood pressure) during cycling with AG exposure. Greater maximum HR responses were observed in men with AG exposure. This novel individualized exercise and orthostatic training protocol was successful in providing each participant with equally strenuous cardiovascular stimuli close to their tolerance limits regardless of individual and sex differences.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.