Evidence map›Paper›PMID 41291852›Full record

ArticleJournal of eating disorders2025

Bidirectional associations between anxiety and eating disorder symptoms in adolescence: the moderating role of childhood household dysfunction.

Guiyu Jiang, Shuyi Peng, Junmin Zhong, Yannan Guo, Qianyu Liu, Yanhong Zhou, Lan Guo

Abstract read
In one paragraph

Article in Journal of eating disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Disordered eating behaviours and their associated factors in adults with type 2 diabetes: A multicentre cross-sectional study.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guiyu JiangDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen University, 74 Zhongshan Road 2, Guangzhou, 510080, People's Republic of China.
Shuyi PengDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen University, 74 Zhongshan Road 2, Guangzhou, 510080, People's Republic of China.
Junmin ZhongDepartment of Obstetrics, First Affiliated Hospital of Jinan University, Guangzhou, People's Republic of China.
Yannan GuoDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen University, 74 Zhongshan Road 2, Guangzhou, 510080, People's Republic of China.
Qianyu LiuDepartment of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen University, 74 Zhongshan Road 2, Guangzhou, 510080, People's Republic of China.
Yanhong Zhou *Guangzhou Women and Children's Medical Center, Guangzhou Medical University, 9 Jinsui Road, Guangzhou, 510623, People's Republic of China. zhouyanhong8383@126.com.
Lan Guo *Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen University, 74 Zhongshan Road 2, Guangzhou, 510080, People's Republic of China. guolan3@mail.sysu.edu.cn.

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2025A1515012576Natural Science Foundation of China 82473652
6 · The paper itself

Abstract

backgroundAnxiety and eating disorder (ED) symptoms often emerge during adolescence and frequently co-occur, considerably impairing the physical health and psychosocial functioning. Previous research has largely focused on assessing only one direction of the association between anxiety and ED symptoms. Limited understanding exists regarding the potential bidirectional associations and the role of childhood household dysfunction (CHD) in this association. This study aims to examine the bidirectional association between anxiety and ED symptoms in adolescents and further explore whether CHD moderates this association.

methodsThis longitudinal study was conducted among students from nine high schools in China. A total of 8,703 participants (mean [SD] age at baseline, 15.89 [0.60] years; 47.4% female) completed the self-reported questionnaires at baseline (June-August 2023) and at a 4-month follow-up (October-December 2023). Anxiety symptoms were assessed using the 7-item Generalized Anxiety Disorder Scale, and ED symptoms using the Sick, Control, One, Fat, Food questionnaire. Information on eight indicators of CHD was collected at baseline. Cross-lagged panel models (CLPM) were applied to examine the bidirectional association between anxiety and ED symptoms, and moderation analyses were performed to assess the moderating role of CHD. Bonferroni corrections were applied with significance thresholds adjusted for multiple testing.

resultsThe CLPM results showed that anxiety and ED symptoms exhibit a bidirectional association, with anxiety at baseline predicted subsequent increased ED symptoms (β = 0.13, 95% CI = 0.11-0.15) and ED symptoms at baseline also predicted subsequent increased anxiety symptoms (β = 0.06, 95% CI = 0.04-0.08). The cumulative CHD score was positively associated with both anxiety (β = 0.07, 95% CI = 0.04-0.11) and ED symptoms (β = 0.06, 95% CI = 0.02-0.09) at follow-up, but did not significantly moderate their relationship. Individual CHD indicators demonstrated distinct moderating effects for boys and girls; none of these effects remained significant after Bonferroni correction.

conclusionsThese findings indicate that anxiety and ED symptoms reinforce each other over time, highlighting the potential value of integrated strategies to address both conditions simultaneously. Future research is warranted to clarify the mechanisms underlying this bidirectional association, explore additional moderating factors, and develop targeted prevention strategies.

Indexed as

AdolescentsAnxiety symptomsChildhood household dysfunctionCross-lagged modelEating disorder symptoms

Identifiers

PMID41291852
PMCPMC12750753

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.