Evidence map›Paper›PMID 41292803›Full record

ArticlebioRxiv : the preprint server for biology2025

Phage N4 uses a SAR endolysin-holin system for host cell lysis.

Michael B Awuah, Cody Martin, Jake S Chamblee, Adam J Tomaszewski, Teresa E Sullivan, Qori Emilia, Steven Tran, Jason H Snowden, Kaylyn A Niemiec, Jiatong Zhu and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Michael B AwuahDepartment of Biology, Center for Phage Technology, Texas A&M University, College Station, Texas, USA.
Cody MartinDepartment of Biochemistry and Biophysics, Center for Phage Technology, Texas A&M University, College Station, Texas, USA.ORCID 0000-0001-7610-9537
Jake S ChambleeDepartment of Biochemistry and Biophysics, Center for Phage Technology, Texas A&M University, College Station, Texas, USA.
Adam J TomaszewskiDepartment of Biochemistry and Biophysics, Center for Phage Technology, Texas A&M University, College Station, Texas, USA.
Teresa E SullivanDepartment of Biochemistry and Biophysics, Center for Phage Technology, Texas A&M University, College Station, Texas, USA.
Qori EmiliaDepartment of Biology, Center for Phage Technology, Texas A&M University, College Station, Texas, USA.
Steven TranDepartment of Biochemistry and Biophysics, Center for Phage Technology, Texas A&M University, College Station, Texas, USA.
Jason H SnowdenDepartment of Biochemistry and Biophysics, Center for Phage Technology, Texas A&M University, College Station, Texas, USA.
Kaylyn A NiemiecDepartment of Biology, Center for Phage Technology, Texas A&M University, College Station, Texas, USA.
Jiatong ZhuDepartment of Biology, Center for Phage Technology, Texas A&M University, College Station, Texas, USA.
Jolene RamseyDepartment of Biology, Center for Phage Technology, Texas A&M University, College Station, Texas, USA.ORCID 0000-0002-3774-5896

Funding

ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale ModelingR01GM129325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2018 to 2025
$5.2M
Phage LysisR35GM136396 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI YOUNG, RYLAND FLETCHER · 2020 to 2024
$1.9M
NIGMS NIH HHS R01 GM129325NIGMS NIH HHS R35 GM136396
6 · The paper itself

Abstract

Bacteriophages (phages) cause active host cell lysis to terminate their infection and release progeny into the environment. Some phages delay their lysis, and thereby increase progeny yield, in a phenomenon called lysis inhibition (LIN). There are two dissimilar phages of

Indexed as

bacteriophageendolysinEscherichia coliholinlysismembraneN4Schitoviridaespanin

Identifiers

PMID41292803
PMCPMC12642591

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.