ReviewRSC advances2025
A comprehensive review on the anti-cancer properties of sesame lignans: chemical composition, molecular mechanisms and prospects.
Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- From Aryltetralin Anticancer Scaffolds to Host-Directed Bioactivities: A Mechanism-Based Review of Lignans and Neolignans.International journal of molecular sciences · 2026Review
- Antioxidant and Cytotoxic Potential of an Undescribed Lignan Isolated From the Pooled Stem and Leaf Extract of Conocarpus lancifolius.Chemistry & biodiversity · 2026Article
- Sample Preparation and Separation of Lignans by Liquid Chromatography.Journal of separation science · 2026Review
- Nutritional Impact on Breast Cancer in Menopausal and Post-Menopausal Patients Treated with Aromatase Inhibitors.Cancers · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review presents a comprehensive report on recent advances in the chemical composition, structures, and diversity of sesame lignans, as well as their anti-cancer properties and underlying molecular mechanisms. An in-depth examination of preclinical and clinical evidence pertaining to the role of sesame lignans in chemotherapy and chemoprevention, focusing on reports of the effects on various indicators of cancer, including cell proliferation, cytotoxicity, apoptosis, invasion, migration, metastasis, signaling pathways,
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.