Evidence map›Paper›PMID 41294536›Full record

ArticleGels (Basel, Switzerland)2025

Antibacterial and Biocompatible Penicillin-Streptomycin Loaded Bacterial Cellulose (BC) Hydrogels for Wound Healing.

Sanosh Kunjalukkal Padmanabhan, Maria Elena Giordano, Stefania Villani, Gayatri Udayan, Mariangela Stoppa, Pietro Alifano, Christian Demitri, Maria Giulia Lionetto, Antonio Licciulli

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sanosh Kunjalukkal PadmanabhanDepartment of Experimental Medicine, University of Salento, 73100 Lecce, Italy.
Maria Elena GiordanoDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.
Stefania VillaniDepartment of Engineering for Innovation, University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-2562-4341
Gayatri UdayanDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0000-0001-6032-4742
Mariangela StoppaDepartment of Engineering for Innovation, University of Salento, 73100 Lecce, Italy.
Pietro AlifanoDepartment of Experimental Medicine, University of Salento, 73100 Lecce, Italy.
Christian DemitriDepartment of Experimental Medicine, University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-1145-6674
Maria Giulia LionettoDepartment of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, 73100 Lecce, Italy.ORCID 0000-0003-3752-0192
Antonio LicciulliDepartment of Engineering for Innovation, University of Salento, 73100 Lecce, Italy.

Funding

POR PUGLIA FESR-FSE 2014/2020 8AE55352
6 · The paper itself

Abstract

Bacterial cellulose (BC) hydrogel is a promising skin wound healing biomaterial due to its unique properties, including a moist environment that facilitates tissue healing. To enhance its antimicrobial efficacy, BC dressings were loaded with penicillin and streptomycin. FT-IR analysis confirmed successful drug binding, while SEM revealed a nanofibrous and porous hydrogel structure. In vitro studies using 3T3 mouse fibroblasts demonstrated biocompatibility, and scratch wound assays achieved complete closure across all tested concentrations. Antibacterial activity, assessed via agar diffusion against

Indexed as

antibacterialantibioticbacterial cellulosehydrogelwound healing

Identifiers

PMID41294536
PMCPMC12652342

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.