Evidence map›Paper›PMID 41294566›Full record

ArticleGels (Basel, Switzerland)2025

Development and Characterization of a Wound-Healing System Based on a Marine Biopolymer.

Catalina Natalia Cheaburu Yilmaz, Melisa Sirin Yildirim, Defne Govem, Hulya Ayar Kayali, Onur Yilmaz

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Catalina Natalia Cheaburu YilmazBiochemistry Division, Department of Chemistry, Faculty of Science, Dokuz Eylül University, 35390 Buca, Izmir, Türkiye.ORCID 0000-0001-5229-8986
Melisa Sirin YildirimBiochemistry Division, Department of Chemistry, Faculty of Science, Dokuz Eylül University, 35390 Buca, Izmir, Türkiye.
Defne GovemDokuz Eylül Üniversitesi İzmir Uluslararası Biyotıp ve Genom Enstitüsü; 35340 Balçova, Izmir, Türkiye.
Hulya Ayar KayaliBiochemistry Division, Department of Chemistry, Faculty of Science, Dokuz Eylül University, 35390 Buca, Izmir, Türkiye.
Onur YilmazLeather Engineering Department, Faculty of Engineering, Ege University, 35100 Bornova, Izmir, Türkiye.ORCID 0000-0002-0992-5937

Funding

Scientific and Technological Research Council of Turkey 2209B -1139B412303160
6 · The paper itself

Abstract

Marine algae are a sustainable and eco-friendly resource, growing rapidly without freshwater or arable land while aiding carbon sequestration. Their extract is rich in biodegradable polysaccharides like alginate, fucoidan, carrageenan, agar, and Ulvan which can be used further in wound healing thanks to their unique characteristics such as ensuring moisture balance and tissue regeneration by forming biocompatible hydrogels with antimicrobial, anti-inflammatory, and antioxidant properties, key requirements in wound healing. The present study explored the utilization of local grown marine algae (i.e., Aegean seashores from Türkiye) and transforming the waste into useful end-products for dermatocosmetics and healing systems. The extracted polyssacharide, e.g., Ulvan which was characterized by means of FT-IR spectroscopy, DSC, and antioxidant activity, was included inside a semi-solid formulation and combined with other polysaccharides from other natural sources such a chitosan, alginate, and hyaluronic acid to form bioactive hydrogels with wound closure activity. The formulated hydrogels exhibited significant swelling capacity, antioxidant activity, and the selected optimal formulation exhibited enhanced wound closure rates in vitro, demonstrating potential for wound-healing applications.

Indexed as

biopolymer modificationboric acidmarine algaeUlvan polysaccharidewound healing

Identifiers

PMID41294566
PMCPMC12652674

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.