Evidence map›Paper›PMID 41294594›Full record

ArticleGels (Basel, Switzerland)2025

Phospholipid-Based Ultraflexible Nanovesicular Gel of Sertaconazole Nitrate for the Treatment of Skin Fungal Infections: Statistical Optimization, In Vitro and Preclinical Assessment.

Malleswara Rao Peram, Sachin R Patil, Vidyadhara Suryadevara, Srinivasa Rao Yarguntla, Smita Kamalakar, Preeti Patil, Kamala Kumari Paravastu, Anand Vishwas Deshmukh, Manohar Kugaji, Sameer Nadaf

Erratum issuedAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Malleswara Rao PeramDepartment of Pharmaceutics, Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Guntur 522019, Andhra Pradesh, India.ORCID 0000-0002-1984-6538
Sachin R PatilDepartment of Pharmaceutics, Sarojini College of Pharmacy, Kolhapur 416004, Maharashtra, India.ORCID 0000-0003-1476-5277
Vidyadhara SuryadevaraDepartment of Pharmaceutics, Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Guntur 522019, Andhra Pradesh, India.ORCID 0000-0002-8804-8003
Srinivasa Rao YarguntlaDepartment of Pharmaceutics, Vignan Institute of Pharmaceutical Technology, Visakhapatnam 530049, Andhra Pradesh, India.ORCID 0000-0002-8803-9668
Smita KamalakarDepartment of Pharmaceutics, Sarojini College of Pharmacy, Kolhapur 416004, Maharashtra, India.
Preeti PatilDepartment of Pharmaceutics, Sarojini College of Pharmacy, Kolhapur 416004, Maharashtra, India.
Kamala Kumari ParavastuDepartment of Pharmaceutics, Vignan Institute of Pharmaceutical Technology, Visakhapatnam 530049, Andhra Pradesh, India.ORCID 0000-0001-9035-4731
Anand Vishwas DeshmukhDepartment of Pharmaceutics, KLE College of Pharmacy, KLE Academy of Higher Education and Research, Belagavi 590010, Karnataka, India.ORCID 0009-0002-5432-1881
Manohar KugajiCentral Research Laboratory, Maratha Mandal's Nathajirao G. Halgekar Institute of Dental Sciences & Research Centre, Belagavi 590010, Karnataka, India.ORCID 0000-0001-6315-4531
Sameer NadafDepartment of Pharmaceutics, Bharati Vidyapeeth College of Pharmacy, Palus 416310, Maharashtra, India.ORCID 0000-0002-7132-1886

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sertaconazole nitrate (SN), a broad-spectrum antifungal agent, is clinically employed against diverse dermatophyte infections. Its therapeutic efficacy, however, is constrained by poor aqueous solubility (0.006 mg/mL) and insufficient skin penetration from current commercial formulations. To address these limitations, this research focused on developing, optimizing (using a 3

Indexed as

antifungal agentfactorial designnanovesicular gelsertaconazole nitrateultraflexible liposomes

Identifiers

PMID41294594
PMCPMC12652887

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.