ReviewJournal of functional biomaterials2025
The Role and Involvement of Functional Three-Dimensional Porcine-Derived Collagen Matrix Biomaterials in Periodontal Regeneration: A Comprehensive Review.
Review in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Cell-Based Biosensors in Oral Health: Emerging Tools for Rapid Detection and Monitoring of Oral Diseases.Biosensors · 2026Review
- Natural Bioactive Compounds in Dental Materials: Balancing Biological Activity and Functional Properties.Pharmaceutics · 2026Review
- Hyaluronic Acid-Based Gels and Biomaterial Systems for Oral Wound Healing: Design and Clinical Translation.Gels (Basel, Switzerland) · 2026Review
- Peri-Implant Soft-Tissue Augmentation Using Xenogeneic Collagen MatricesJournal of oral & maxillofacial researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Three-dimensional porcine matrix-derived biomaterials have emerged as valuable tools in periodontal regeneration, offering structural stability, biocompatibility, and favorable cellular responses. This review summarizes their physicochemical characteristics, biological mechanisms, and clinical performance in guided tissue and bone regeneration. Comparative analyses show superior handling, integration potential, and regenerative predictability compared with collagen and synthetic scaffolds, especially in complex intrabony and furcation defects. Despite promising clinical outcomes, heterogeneity in processing techniques and limited long-term data still hinder standardization. Overall, porcine-derived scaffolds represent reliable and biologically active options for periodontal regeneration. Future innovation focusing on functionalization, cell integration, and patient-tailored design will define the next generation of predictable and biomimetic regenerative solutions.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.