Profoundly Uncontrolled Diabetes Mellitus and Social Disadvantage Among Hospitalized Patients with Mucormycosis in Central California.

Almira Opardija, Krishna Ragavachari Suresh, Pavel Diaz, Yueqi Yan, Geetha Sivasubramanian

Abstract read

In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Almira OpardijaDivision of Infectious Diseases, Department of Medicine, University of California San Francisco, Fresno, CA 93701, USA.ORCID 0000-0002-0089-6252

Krishna Ragavachari SureshDepartment of Internal Medicine, University of South Dakota, Vermillion, SD 57069, USA.ORCID 0009-0009-8456-2468

Pavel DiazSchool of Engineering, University of California, Merced, CA 95343, USA.

Yueqi YanHSRI Biostatistics and Data Support Core, University of California, Merced, CA 95343, USA.

Geetha SivasubramanianDivision of Infectious Diseases, Department of Medicine, University of California San Francisco, Fresno, CA 93701, USA.ORCID 0000-0002-8443-7095

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucormycosis (MCM) is an opportunistic fungal infection in immunocompromised hosts, most commonly associated with poorly controlled diabetes mellitus (DM). We conducted a retrospective review of 45 MCM cases diagnosed between 2010 and 2023 at a referral center in Central California, a region with high DM prevalence and significant healthcare disparities. Clinical features, histopathology, microbiology, treatment, and outcomes were analyzed. Ninety-six percent of patients had DM, and 69% had no other predisposing condition. Glycemic control was markedly poor: 36% had HbA1c > 10%, and 61% had HbA1c > 8%. Diabetic ketoacidosis (DKA) was present in 19% of patients and associated with 100% mortality. Rhino-orbito-cerebral mucormycosis (ROCM) accounted for 60% of cases and carried a 70% mortality rate. Angioinvasion, confirmed in 62% of biopsied cases, significantly increased mortality (69% vs. 28%,

Indexed as

mucormycosissocial deprivationuncontrolled diabetes mellitus

Identifiers

PMID41295146

DOI10.3390/jof11110765

PMCPMC12653091

What Socratic holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.