Evidence map›Paper›PMID 41295504›Full record

ArticleVaccines2025

COVID-19 Vaccination, Hospitalization Rates, and Mortality Differ Between People with Diagnosed Immune Mediated Inflammatory Disease and the General Population: A Population-Based Study.

Carol A Hitchon, Carole Taylor, Charles N Bernstein, Christine A Peschken, Diane Lacaille, Gilaad G Kaplan, Jessica Widdifield, Ruth Ann Marrie

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carol A HitchonDepartment of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0001-5547-3268
Carole TaylorManitoba Centre for Health Policy, Community Health Sciences, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Charles N BernsteinDepartment of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0001-8041-3574
Christine A PeschkenDepartment of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0002-4269-5213
Diane LacailleArthritis Research Canada and Division of Rheumatology, Department of Medicine, University of British Columbia, Vancouver, BC V5Y 3P2, Canada.ORCID 0000-0002-4065-4151
Gilaad G KaplanDepartments of Medicine and Community Health Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0003-2719-0556
Jessica WiddifieldSunnybrook Research Institute, ICES, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON M5S 1A1, Canada.ORCID 0000-0002-7464-0460
Ruth Ann MarrieDepartments of Medicine and Community Health and Epidemiology, Dalhousie University, Nova Scotia Health, Halifax, NS B3H 1V7, Canada.ORCID 0000-0002-1855-5595

Funding

Public Health Agency of Canada- COVID-19 Immunity Task Force. 2122-HQ-000070
6 · The paper itself

Abstract

backgroundVaccination reduces Coronavirus disease-19 (COVID-19) infection severity. We evaluated COVID-19 vaccine uptake and effectiveness in people with immune mediated inflammatory diseases (pIMIDs) versus the general population.

methodsUsing population-based administrative health records, we identified cohorts between 2004 and 2022 with an IMID (rheumatoid arthritis

resultsMore pIMIDs were vaccinated than comparators (87.3% vs. 84.7%,

conclusionsAlthough COVID-19 vaccination reduced the risk of Hosp-C and death in both pIMIDs and comparators, pIMIDs remained at higher risk for both. Since SARS-CoV-2 is now endemic, these findings may inform ongoing vaccination recommendations.

Indexed as

administrative health dataCOVID-19hospitalizationimmune mediated inflammatory diseaseinflammatory bowel diseasemortalitymultiple sclerosispsoriasisrheumatoid arthritissystemic autoimmune rheumatic diseasevaccine

Identifiers

PMID41295504
PMCPMC12656540

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.