Evidence map›Paper›PMID 41295688›Full record

ReviewVeterinary sciences2025

Targeting the Gut-Mammary Axis for Understanding Mastitis Pathogenesis and Therapeutic Strategies.

Yan Li, Menghan Wang, Wenqiang Liu, Mingyang Geng, Mohammed Asiri, Fuad M Alzahrani, Khalid J Alzahrani, Qingshan Ma, Changfa Wang, Muhammad Zahoor Khan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yan LiCollege of Agriculture and Biology, Liaocheng University, Liaocheng 252000, China.
Menghan WangCollege of Agriculture and Biology, Liaocheng University, Liaocheng 252000, China.
Wenqiang LiuCollege of Agriculture and Biology, Liaocheng University, Liaocheng 252000, China.ORCID 0000-0001-5028-0467
Mingyang GengYili Kazak Autonomous Prefecture Livestock General Station, Yili 835000, China.
Mohammed AsiriDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia.ORCID 0000-0002-8677-9240
Fuad M AlzahraniDepartment of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi Arabia.ORCID 0000-0001-6930-5214
Khalid J AlzahraniDepartment of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, Taif 21944, Saudi Arabia.ORCID 0000-0002-6688-0106
Qingshan MaCollege of Agriculture and Biology, Liaocheng University, Liaocheng 252000, China.
Changfa WangCollege of Agriculture and Biology, Liaocheng University, Liaocheng 252000, China.
Muhammad Zahoor KhanCollege of Agriculture and Biology, Liaocheng University, Liaocheng 252000, China.ORCID 0000-0001-5890-2996

Funding

Deanship of Scientific Research at King Khalid University, the large research group program R.G.P.02/709/46Liaocheng Municipal Bureau of Science and Technology, High-talented Foreign Expert Introduction Program GDWZ202401Livestock and Poultry Breeding Industry Project of the Ministry of Agriculture and Rural Affairs 19211162National Key R&D Program of China 2022YFD1600103; 2023YFD1302004Shandong Province Agricultural Major Technology Collaborative Promotion Plan SDNYXTTG-2024-13
6 · The paper itself

Abstract

Mastitis represents one of the most economically devastating diseases in dairy production, causing billions of dollars in annual losses through reduced milk quality and quantity. Recent advances in microbiome research have unveiled a critical gut-mammary axis that fundamentally influences mastitis susceptibility and pathogenesis in dairy cattle. Through comprehensive analysis of microbial communities across multiple anatomical sites, we demonstrate that mastitis development involves systematic disruption of both mammary and gastrointestinal microbiomes, characterized by reduced beneficial bacterial populations and increased pathogenic species. Healthy animals maintain balanced microbial ecosystems dominated by protective taxa including

Indexed as

dairy cattledysbiosisgut–mammary axisinflammationmicrobiomeudder health

Identifiers

PMID41295688
PMCPMC12656805

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.