Evidence map›Paper›PMID 41295746›Full record

ArticleVeterinary sciences2025

Genetic Characterization of the First Case of Lumpy Skin Disease in Singapore, 2022.

Eileen Y Koh, Adrian K S Tan, Yin Cheong Aden Ip, Clara Lau, Jasmine Ong, Oi Wing Ng, Jing Chen, Christine Lee, Suria Fabbri, Juline Chua and 7 more

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Eileen Y KohAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.ORCID 0000-0002-9378-6334
Adrian K S TanAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.ORCID 0000-0001-5872-7120
Yin Cheong Aden IpAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.
Clara LauAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.
Jasmine OngAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.
Oi Wing NgAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.
Jing ChenAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.ORCID 0000-0003-0835-2396
Christine LeeAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.
Suria FabbriAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.
Juline ChuaAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.
Samyuktha BalakumarAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.
Kelvin HoAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.ORCID 0009-0004-1970-1082
Wai Kwan WongAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.ORCID 0000-0001-5480-4109
Brian Z Y TanAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.
Charlene Judith FernandezAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.
Siow Foong ChangAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.
Him Hoo YapAnimal and Veterinary Service, National Parks Board, Singapore Botanic Gardens, 1 Cluny Road, Singapore 259569, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lumpy Skin Disease (LSD) is a transboundary viral disease of wild and domesticated ruminants, and notifiable to the World Organisation for Animal Health (WOAH). LSD has spread rapidly in the cattle population across the African, European and Asian continents since 1929. Following recent outbreaks in the Southeast Asia region, Singapore observed its first occurrence of LSD in a local dairy cattle farm in March 2022. LSD was confirmed in dairy cattle exhibiting clinical signs with quantitative real-time PCR and sequencing with MinION Nanopore. Analyses of the assembled whole viral genomes also revealed high phylogenetic relatedness to LSD recombinant strains. It remains unclear how the virus was introduced into Singapore, given the absence of known vectors and strict import regulations in place. This highlights the importance of biosurveillance, and laboratory diagnostic readiness to manage outbreaks and prevent the spread of transboundary diseases.

Indexed as

Lumpy Skin Diseasemolecular detectionnext generation sequencingoutbreak detectionSingapore

Identifiers

PMID41295746
PMCPMC12656970

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.