Evidence mapPaperPMID 41298265Full record

Trial reportBMJ open2025

Methods and baseline results of the Cohort of Health-Related Outcomes in Chronic Illness Care in General Practice in Denmark (CHRONIC-GP).

Henrik Hp Larsen, Tora G Willadsen, Anders Prior, Anna B Lyhnebeck, Frans B Waldorff, Anne Holm

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05676541 (Effectiveness of an Adaptive, Complex Intervention to Enhance Care for Patients With Complex Multimorbidity in General Practice - a Pragmatic Cluster Randomized Controlled Trial), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05676541 nacompletednot on this map

Effectiveness of an Adaptive, Complex Intervention to Enhance Care for Patients With Complex Multimorbidity in General Practice - a Pragmatic Cluster Randomized Controlled Trial

TypeinterventionalSponsorUniversity of CopenhagenRan2023 to 2025Enrolled117,000ConditionsMultimorbidityArmsComplex intervention to enhance care for patients with multimorbidity in general practice consisting of an extended overview consultation and supporting elements
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Henrik Hp LarsenResearch Unit of General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark henrikhpl@hotmail.com.ORCID http://orcid.org/0009-0008-2042-1503
Tora G WilladsenResearch Unit of General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-7240-1944
Anders PriorResearch Unit for General Practice, Aarhus University, Aarhus, Denmark.ORCID http://orcid.org/0000-0003-4053-3701
Anna B LyhnebeckResearch Unit of General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Frans B WaldorffResearch Unit of General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Anne HolmResearch Unit of General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-3819-3429

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe Cohort of Health-Related Outcomes in Chronic Illness Care in General Practice was established using data collected as part of a cluster-randomised trial. This aims to support the trial's follow-up and enable further examination of the interplay between chronic disease, multimorbidity (MM), polypharmacy (PP) and quality of life (QoL) in a Danish general practice setting.

participantsThe cohort comprises 35 977 adult patients from 250 general practices participating in a cluster-randomised trial and had a response rate of 22.4%. Participants were either registered as chronic care patients or had attended an annual chronic disease consultation. They completed a comprehensive questionnaire on self-reported chronic conditions, medication use, QoL, treatment burden and patient-centred care. Additionally, 431 general practitioners (GPs) from the participating practices completed a questionnaire about managing patients with complex MM. FINDINGS TO DATE: Among participants, 51.9% were female, the mean age was 65.6 (SD 12.9) years, 93.1% had education beyond basic schooling, and half were retired. Conditions from more than one organ system-based disease group were reported by 82.2%, and 94.6% used one or more prescription medications. The main challenges reported by the participating GPs in managing patients with complex MM were keeping time and obtaining an overview of the patient's health status. FUTURE PLANS: Cohort data will be linked with Danish registries to improve the detection and treatment of chronic conditions and PP in general practice. REGISTRATION: The cluster randomised trial (MM600) is registered with ClinicalTrials.gov ID: NCT05676541.

Indexed as

General PracticeQuality of LifeAdultAgedChronic DiseaseCohort StudiesDenmarkFemaleHumansMaleMiddle AgedMultimorbidityPatient-Centered CarePolypharmacySurveys and QuestionnairesEPIDEMIOLOGIC STUDIESGeneral PracticeMultimorbidityPrimary Health CareQuality of Life

Identifiers

PMID41298265
PMCPMC12658489

What Socratic holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.