Evidence map›Paper›PMID 41299126›Full record

Trial reportObesity surgery2026

Postoperative Spirulina Platensis Supplementation Optimizes Body Composition Improvement without Adverse Effects in Women Undergoing Gastric Bypass: a Pilot Study Randomized and Placebo-Controlled.

Paula Caroline de Almeida, Thiago da Rosa Lima, Eudes Thiago Pereira Avila, Gabriel Abreu Brito, Natália Ost Malheios, Régis Vilela Leal, Eduardo Rodrigues Alves Junior, Gunther Peres Pimenta, James Wilfred Navalta, Amilcar Sabino Damazo

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Paula Caroline de AlmeidaPost-Graduation Program in Health Sciences, Faculty of Medicine, Federal University of Mato Grosso, Cuiabá, Brazil.
Thiago da Rosa LimaPost-Graduation Program in Health Sciences, Faculty of Medicine, Federal University of Mato Grosso, Cuiabá, Brazil. limars.thiago@gmail.com.
Eudes Thiago Pereira AvilaPost-Graduation Program in Health Sciences, Faculty of Medicine, Federal University of Mato Grosso, Cuiabá, Brazil.
Gabriel Abreu BritoFaculty of Medicine, University Center of Várzea Grande, Várzea Grande, Brazil.
Natália Ost MalheiosFaculty of Medicine, University Center of Várzea Grande, Várzea Grande, Brazil.
Régis Vilela LealFaculty of Medicine, University Center of Várzea Grande, Várzea Grande, Brazil.
Eduardo Rodrigues Alves JuniorFaculty of Medicine, University Center of Várzea Grande, Várzea Grande, Brazil.
Gunther Peres PimentaPost-Graduation Program in Health Sciences, Faculty of Medicine, Federal University of Mato Grosso, Cuiabá, Brazil.
James Wilfred NavaltaDepartment of Kinesiology and Nutrition Sciences, University of Nevada-Las Vegas, Las Vegas, NV, USA.
Amilcar Sabino DamazoPost-Graduation Program in Health Sciences, Faculty of Medicine, Federal University of Mato Grosso, Cuiabá, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRoux-en-Y gastric bypass (RYGB) is an effective treatment for obesity and metabolic disorders. Co-administration of Spirulina (SP), a cyanobacterium of the genus Arthrospira platensis, accelerates weight loss and improves body composition. It is believed that supplementing with 2 g of SP for 30 days is safe and improves body composition in women undergoing RYGB.

objectiveTo evaluate the effects of SP supplementation on body composition and blood parameters of women undergoing RYGB.

methodsForty-nine women indicated for RYGB were divided into two groups: SP (n =25), which received 2 g of SP, and placebo (PL, n =24), which received 2 g of starch. The parameters were analyzed at baseline and after 30 days of post-RYGB intervention. ANCOVA and chi-square were performed in SPSS (version 25), with a significance level of 5% (p < 0.05).

resultsThirty patients (SP, n = 15; PL, n = 15) with a mean age of 42.82±9.35 years concluded the study. Post-RYGB, the SP group exhibited significant decreases in arm circumference (p = 0.035), fat mass (p = 0.033), muscle mass loss (p <0.001), body fat (p = 0.018), subcutaneous fat (p = 0.019), and blood urea levels (p = 0.042) compared to the PL group. The SP group had significantly more lean mass (p = 0.036) and skeletal muscle mass (p = 0.030), elevated BMR (p = 0.034), and a higher percentage of fat mass loss (p <0.001), along with increased levels of body protein (p = 0.028) and hydration (p = 0.037) in comparison to the PL group.

conclusionSupplementation with 2 g of SP for 30 days was safe, improved body composition, and decreased urea levels in women with obesity undergoing RYGB.

Indexed as

Body CompositionDietary SupplementsGastric BypassObesity, MorbidSpirulinaAdultFemaleHumansMiddle AgedPilot ProjectsPostoperative CareTreatment OutcomeWeight LossBody compositionObesity managementPerioperative careRoux-en-Y gastric bypassSpirulina

Identifiers

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.