Evidence map›Paper›PMID 41299376›Full record

ArticleBMC women's health2025

Anthropometric indices and mortality in postmenopausal women: NHANES 1999-2018 evidence.

Kexin Wang, Yanhua Li, Yu Chen

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Article in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Kexin WangThe Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, 310005, China. kexinwang0899@163.com.
Yanhua LiThe Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, 310005, China.
Yu ChenYingfeng Community Health Center, Hangzhou, Zhejiang Province, 311215, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited research has focused on how anthropometric measures relate to mortality risk, specifically among postmenopausal women. Our study aimed to explore the association between anthropometric indices and risks of all-cause and cardiovascular mortality in American postmenopausal women.

methodsData from the NHANES cycles 1999-2018 were extracted. Firstly, weighted multivariable Cox proportional hazards models and restricted cubic splines (RCS) were used to detect the association between six body indicators, including body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), a body shape index (ABSI), body roundness index (BRI), and weight-adjusted waist index (WWI), and all-cause and CVD mortality risk in postmenopausal women. Furthermore, the predictive power of different anthropometric indices for mortality was assessed by time-dependent receiver operator characteristic (ROC) curves. Subgroup and sensitivity analyses were further employed to evaluate the consistency and robustness of the findings.

resultsDuring an average follow-up of 10.04 years, 2522 deaths were reported from any cause, and 783 participants died of CVD in total. A fully adjusted multivariate Cox regression model indicated a significant positive association between WWI and ABSI and all-cause and CVD mortality in postmenopausal Americans. The RCS revealed a significant nonlinear relationship between BRI and WC and all-cause mortality, whereas the relationships between WWI and ABSI and CVD/all-cause mortality were positively linear. For all-cause mortality prediction, WWI outperformed other anthropometric parameters, with an AUC of 0.616 (95% CI 0.594-0.637) for 5 year, 0.624 (95% CI 0.608-0.640) for 10-year, and 0.641 (95% CI 0.624-0.658) for 15-year. Consistently, WWI showed the highest AUC of 0.642 (95% CI 0.605-0.679), 0.656 (95% CI 0.631-0.681)and 0.675 (95% CI 0.651-0.699) when predicting 5-year, 10-year and 15-year CVD mortality, respectively. Subgroup and sensitivity analyses confirmed the stability and robustness of our findings.

conclusionHigher ABSI and WWI values were linearly associated with increased all-cause and CVD mortality in postmenopausal women in the U.S. WWI and ABSI anthropometric indicators may be useful tools to detect CVD and all-cause mortality risks and to support early intervention strategies for individuals after menopause in clinical practice.

Indexed as

AnthropometryCardiovascular DiseasesMortalityPostmenopauseAgedBody Mass IndexCause of DeathFemaleHumansMiddle AgedNutrition SurveysProportional Hazards ModelsRisk FactorsUnited StatesWaist CircumferenceWaist-Height RatioBody compositionCardiovascular diseaseMenopauseMortalityObesity

Identifiers

PMID41299376
PMCPMC12751837

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.