Trial reportJournal of neuroengineering and rehabilitation2025
Effects of unilateral lower limb exoskeleton robot on gait improvement and brain function in patients with chronic stroke: a randomized clinical trial.
Trial report in Journal of neuroengineering and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Acupuncture combined with rehabilitation robot for recovery of hemiplegia after ischemic stroke: systematic review and meta-analysis of randomized controlled trials.Frontiers in neurologyPooled it
- Integrative Rehabilitation for War-Related Polytrauma: A Narrative Review of Multidimensional Strategies and Implementation Challenges.Healthcare (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectiveThis study aimed to observe the efficacy of unilateral lower limb exoskeleton robot training and its effect on neuroplasticity in hemiplegic patients with stroke by comparing it with conventional treatment.
methodsTwenty-four patients with chronic stroke were randomly assigned to either the robot group (RG) or the control group (CG). The CG was treated with conventional rehabilitation, and the RG was treated with unilateral lower limb exoskeleton robot-assisted walking training based on conventional rehabilitation. The study’s primary outcome measures included gait analysis and plantar pressure testing before and after treatment. Secondary outcome measures included changes in lower limb Fugl-Meyer (FMA), Timed Up and Go Test (TUG), and Modified Barthel Index (MBI). In addition, we used functional near - infrared spectroscopy (fNIRS) to measure neural activity before and after the intervention.
resultsThe robot group had significantly greater improvements in walking speed and stride length compared to the control group. The robot group showed greater improvements in FMA scores and reductions in TUG duration compared to the control group. Changes in plantar pressure and oxyhemoglobin (HbO) concentrations were observed only in the robot group.
conclusionBoth conventional rehabilitation therapy and robot-assisted gait training improve walking function in patients with chronic stroke, but robot-assisted intervention shows more favorable outcomes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.