Evidence map›Paper›PMID 41299745›Full record

SynthesisJournal of cardiothoracic surgery2025

Predictive role of geriatric nutritional risk index for postoperative complications in operated esophageal cancer patients: a meta-analysis.

Long Tian, Yijie Bu, Yao Wang, Yan Wang, Guowei Che

Abstract readMeta-Analysis
In one paragraph

Synthesis in Journal of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Long TianDepartment of Thoracic Surgery/Lung Cancer Center, West China Hospital, Lung Cancer Center, Sichuan University, Chengdu, 610041, P.R. China.
Yijie BuDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, 610041, P.R. China.
Yao WangDepartment of Thoracic Surgery/Lung Cancer Center, West China Hospital, Lung Cancer Center, Sichuan University, Chengdu, 610041, P.R. China.
Yan WangDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, 610041, P.R. China.
Guowei CheDepartment of Thoracic Surgery/Lung Cancer Center, West China Hospital, Lung Cancer Center, Sichuan University, Chengdu, 610041, P.R. China. cheguoweixw@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the association between preoperative geriatric nutritional risk index (GNRI) and postoperative complications in surgical esophageal cancer patients.

methodsPubMed, Web of Science EMBASE and CNKI databases were searched from inception up to December 16, 2024. Primary outcome was the overall complication. Secondary outcomes included the postoperative pulmonary complication (PPC), anastomotic leakage, chylothorax, vocal code paresis, pneumonia, arrhythmia, incision infection, gastrointestinal complication, respiratory failure and heart failure. Odds ratios (ORs) and 95% confidence intervals (CIs) were combined.

resultsEight eligible studies were included with 1,689 cases. Pooled results demonstrated that lower GNRI was significantly related to increased risk of overall complication (OR = 2.56, 95% CI: 1.85-3.55, P<0.001) and PPC (OR = 2.06, 95% CI: 1.71-2.48, P<0.001). Besides, GNRI was associated with the risk of anastomotic leakage (OR = 1.83, P = 0.007), pneumonia (OR = 3.87, P<0.001) and respiratory failure (OR = 9.71, P = 0.003).

conclusionBased on available evidence, GNRI could serve as a prognostic indicator and a lower GNRI predicted increased incidence of postoperative complications among surgical esophageal cancer patients. However, due to the limitations of this meta-analysis like the small sample size, more high-quality studies are still needed to verify above findings.

trial registrationThis meta-analysis was registered in INSPLAY platform (INPLASY202590012; DOI: https://doi.org/10.37766/inplasy2025.9.0012 ).

Indexed as

Esophageal NeoplasmsEsophagectomyGeriatric AssessmentNutritional StatusNutrition AssessmentPostoperative ComplicationsAgedHumansRisk AssessmentRisk FactorsEsophageal cancerGeriatric nutritional risk indexMeta-analysisPostoperative complication

Identifiers

PMID41299745
PMCPMC12659037

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.