Evidence mapPaperPMID 41299746Full record

ArticleTrials2025

Evaluation of a smartphone app to maintain skin protection behaviour in patients with work-related hand eczema as part of a maintenance programme: protocol for the quasi-randomised controlled trial 'TecNaP-RCT'.

Marc Rocholl, Nele Ristow, Frauke Scheufler, Kathrin Nordheider, Christoph Skudlik, Swen Malte John, Michaela Ludewig, Annika Wilke

Abstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Mental health in occupational dermatology].Dermatologie (Heidelberg, Germany) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marc RochollDepartment of Dermatology, Environmental Medicine and Health Theory, Institute for Health Research and Education, Osnabrück University, Am Finkenhügel 7a, Osnabrück, 49076, Germany. marc.rocholl@uni-osnabrueck.de.ORCID http://orcid.org/0000-0002-6584-0161
Nele RistowDepartment of Dermatology, Environmental Medicine and Health Theory, Institute for Health Research and Education, Osnabrück University, Am Finkenhügel 7a, Osnabrück, 49076, Germany.ORCID http://orcid.org/0000-0003-0900-0595
Frauke ScheuflerDepartment of Dermatology, Environmental Medicine and Health Theory, Institute for Health Research and Education, Osnabrück University, Am Finkenhügel 7a, Osnabrück, 49076, Germany.ORCID http://orcid.org/0009-0005-0537-4305
Kathrin NordheiderDepartment of Dermatology, Environmental Medicine and Health Theory, Institute for Health Research and Education, Osnabrück University, Am Finkenhügel 7a, Osnabrück, 49076, Germany.
Christoph SkudlikDepartment of Dermatology, Environmental Medicine and Health Theory, Institute for Health Research and Education, Osnabrück University, Am Finkenhügel 7a, Osnabrück, 49076, Germany.ORCID http://orcid.org/0000-0002-5670-8396
Swen Malte JohnDepartment of Dermatology, Environmental Medicine and Health Theory, Institute for Health Research and Education, Osnabrück University, Am Finkenhügel 7a, Osnabrück, 49076, Germany.ORCID http://orcid.org/0000-0001-5406-9458
Michaela LudewigFachbereich Gesundheitswissenschaften, Hochschule Bochum, Gesundheitscampus 6-8, Bochum, 44801, Germany.ORCID http://orcid.org/0000-0003-1214-1399
Annika WilkeDepartment of Dermatology, Environmental Medicine and Health Theory, Institute for Health Research and Education, Osnabrück University, Am Finkenhügel 7a, Osnabrück, 49076, Germany.ORCID http://orcid.org/0000-0002-6903-0449

Funding

Institution for Statutory Accident Insurance and Prevention in the Health and Welfare Services 1680
6 · The paper itself

Abstract

backgroundWork-related hand eczema (WRHE) is a common occupational disease in Europe, associated with impaired quality of life and a substantial socioeconomic burden. As skin protection behaviour critically influences disease course, mobile health interventions may help establish and maintain routines. The smartphone app 'Mein Hautschutz im Alltag' (MiA; German for 'My Skin Protection in Everyday Life') was developed to support patients with WRHE, but its clinical effectiveness has not yet been evaluated.

methodsThis quasi-randomised controlled trial will enrol 286 adults with WRHE attending a 3-week inpatient programme at a specialised dermatology clinic. Participants are allocated in clusters based on admission date to either care as usual (control) or care as usual plus an individual goal-setting interview and a 6-month access to the MiA app (intervention). The primary outcome is change in skin protection behaviour from baseline to 6 months post-discharge. Secondary outcomes include clinical and self-rated skin condition, action control, and quality of life. Analyses will follow the intention-to-treat principle using linear mixed models. DISCUSSION: This is the first systematic evaluation of the MiA app's effectiveness in patients with WRHE in a quasi-randomised controlled trial. By combining a structured goal-setting interview with the MiA app, the intervention aims to support the long-term adoption and maintenance of protective behaviours in both occupational and private settings. Key limitations include the quasi-random allocation by admission date (no true randomisation), lack of allocation concealment and blinding, reliance on self-reported primary outcomes, and a 6-month follow-up. Despite these constraints, the pragmatic design aims to generate decision-relevant, real-world evidence for WRHE care.

trial registrationGerman Clinical Trial Registry DRKS00036627. Registered on April 14, 2025.

Indexed as

Dermatitis, OccupationalEczemaHand DermatosesHealth BehaviorMobile ApplicationsSmartphoneGermanyHumansNon-Randomized Controlled Trials as TopicPragmatic Clinical Trials as TopicQuality of LifeTelemedicineTime FactorsTreatment OutcomeGermanyProtocolQuasi-randomised controlled trialSmartphone appWork-related hand eczema

Identifiers

PMID41299746
PMCPMC12670733

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.