SynthesisEuropean journal of medical research2025
Influence of diabetes on short-term mortality of patients with acute type A aortic dissection: a meta-analysis.
Synthesis in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute type A aortic dissection (ATAAD) is a life-threatening cardiovascular emergency with substantial early mortality. Whether diabetes mellitus (DM) independently influences short-term mortality in ATAAD remains uncertain. We conducted a meta-analysis to synthesize the available data.
methodsPubMed, Embase, and Web of Science were searched from inception to June 22, 2025, for longitudinal studies reporting short-term mortality (in-hospital or 30-day) in ATAAD patients with and without DM. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using a random-effects model accounting for the influence of heterogeneity. Subgroup, sensitivity, and meta-regression analyses explored heterogeneity. The study quality was assessed with the Newcastle-Ottawa Scale (NOS).
resultsTwenty-one retrospective cohort studies involving 19,291 patients were included. DM was associated with a modestly increased short-term mortality risk (OR = 1.48; 95% CI 1.14 to 1.91; p = 0.003; I
conclusionsThis meta-analysis of retrospective studies suggests that DM may be associated with higher short-term mortality in ATAAD. Given the observational nature of the evidence, further prospective studies are needed to clarify this relationship.
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