Evidence map›Paper›PMID 41299991›Full record

ArticleFoods (Basel, Switzerland)2025

Protective Effects of Quinic Acid Against Disuse-Induced Skeletal Muscle Atrophy via Regulation of Inflammation and Oxidative Stress.

Mi-Bo Kim, Hyerin Lee, Junhui Kang, Bohkyung Kim, Jae-Kwan Hwang

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Nutrients · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mi-Bo KimDepartment of Food Science and Nutrition, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0009-0006-2598-6066
Hyerin LeeGraduate Program in Bioindustrial Engineering, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.
Junhui KangGraduate Program in Bioindustrial Engineering, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.ORCID 0009-0008-4046-4690
Bohkyung KimDepartment of Food Science and Nutrition, Pusan National University, Busan 46241, Republic of Korea.
Jae-Kwan HwangGraduate Program in Bioindustrial Engineering, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.ORCID 0000-0002-5550-6661

Funding

National Research Foundation of Korea RS-2023-00247455, RS-2024-00463250, RS-2022-NR073930
6 · The paper itself

Abstract

Disuse-induced muscle atrophy (DMA), commonly resulting from immobilization, is driven by chronic inflammation and oxidative stress, which disrupts the balance between protein synthesis and degradation. Quinic acid (QA), a natural compound with known antioxidant and anti-inflammatory properties, was investigated for its potential to counteract muscle atrophy. Using a DMA-induced immobilization model in male C57BL/6N (8 weeks) mice, we found that oral QA administration significantly restored the weight and cross-sectional area of atrophic muscles and improved muscle function, as measured by grip strength and treadmill performance. QA also reduced the expression of pro-inflammatory cytokines (

Indexed as

disuse-induced muscle atrophyinflammationL6 myotubesoxidative stressprotein turnoverquinic acid

Identifiers

PMID41299991
PMCPMC12651271

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.