Evidence map›Paper›PMID 41300023›Full record

ArticleFoods (Basel, Switzerland)2025

Physiologically Relevant Simulation of Carbohydrate Digestion: From Glycemic Index Estimation to Intestinal Cellular Responses.

Jinfeng Meng, Ying Sun, Peng Wu, Zhizhong Dong, Yuhan Qin, Liming Wang, Jie Xiao, Can Hou, Xin Ying, Jiaxing Gao and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jinfeng MengNutrition & Health Research Institute, COFCO Corporation, Beijing 102209, China.
Ying SunNutrition & Health Research Institute, COFCO Corporation, Beijing 102209, China.ORCID 0000-0002-3833-7202
Peng WuLife Quality Engineering Interest Group, Chemical Engineering and Materials Science, School of Chemical and Environmental Engineering, College of Chemistry, Soochow University, Suzhou 215123, China.ORCID 0000-0002-3339-4179
Zhizhong DongNutrition & Health Research Institute, COFCO Corporation, Beijing 102209, China.
Yuhan QinNutrition & Health Research Institute, COFCO Corporation, Beijing 102209, China.ORCID 0000-0001-5622-0537
Liming WangNutrition & Health Research Institute, COFCO Corporation, Beijing 102209, China.
Jie XiaoNutrition & Health Research Institute, COFCO Corporation, Beijing 102209, China.
Can HouNutrition & Health Research Institute, COFCO Corporation, Beijing 102209, China.
Xin YingNutrition & Health Research Institute, COFCO Corporation, Beijing 102209, China.
Jiaxing GaoNutrition & Health Research Institute, COFCO Corporation, Beijing 102209, China.
Meili HuanNutrition & Health Research Institute, COFCO Corporation, Beijing 102209, China.
Ran ChenNutrition & Health Research Institute, COFCO Corporation, Beijing 102209, China.
Yan WangInternational Trade Food Science Research Institute Co., Ltd., Beijing 102209, China.
Yufeng WangInternational Trade Food Science Research Institute Co., Ltd., Beijing 102209, China.
Jingjing WangLife Quality Engineering Interest Group, Chemical Engineering and Materials Science, School of Chemical and Environmental Engineering, College of Chemistry, Soochow University, Suzhou 215123, China.
Xiaodong ChenLife Quality Engineering Interest Group, Chemical Engineering and Materials Science, School of Chemical and Environmental Engineering, College of Chemistry, Soochow University, Suzhou 215123, China.
Tai AnNutrition & Health Research Institute, COFCO Corporation, Beijing 102209, China.

Funding

China Postdoctoral Science Foundation Grant (NO.2016M601239)COFCO Nutrition and Health Research Institute NO. 2015-C2-F007Special Project for Transformation of Scientific and Technological Achievements in Zhangjiakou City 2311005Hcthe National Key Research and Development Program of China 2022YFF1100504
6 · The paper itself

Abstract

Simulating carbohydrate digestion in physiologically relevant ways remains a challenge for in vitro models. In this study, the Dynamic In vitro Human Stomach (DIVHS) system was applied to investigate cereal digestion and subsequent intestinal cellular responses. Rice, millet, and corn were digested under dynamic and static conditions. Compared with the static model, the dynamic system generated smaller grain fragments, a larger chyme-enzyme contact area (451.2 ± 4.4 cm

Indexed as

Caco-2 cellsdynamic digestion modelestimated glycemic indexglucosestatic digestion modeltranscriptome

Identifiers

PMID41300023
PMCPMC12651793

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.