Evidence map›Paper›PMID 41300054›Full record

ReviewFoods (Basel, Switzerland)2025

Advances in pH-Responsive Release Technologies in Food System: Mechanisms, Strategies, Application Forms and Future Directions.

Lidan Zhang, Junjun Zhang, Jianing Zhang, Xiaowei Huang, Jiyong Shi

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lidan ZhangAgricultural Product Processing and Storage Lab, School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Junjun ZhangAgricultural Product Processing and Storage Lab, School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0001-7004-199X
Jianing ZhangAgricultural Product Processing and Storage Lab, School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Xiaowei HuangAgricultural Product Processing and Storage Lab, School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Jiyong ShiAgricultural Product Processing and Storage Lab, School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.

Funding

National Key Research and Development Program of China 2022YFD2100603National Key Research and Development Program of China 2023YFE0105500National Natural Science Foundation of China 32272407National Natural Science Foundation of China 32402185
6 · The paper itself

Abstract

pH-responsive technology enables precise control over the release of functional molecules, thereby maximizing their bioavailability. As the first comprehensive assessment of pH-responsive systems within food science, this review systematically examines the mechanism of pH-triggered release, which covers the protonation and deprotonation of functional groups and the breaking of dynamic covalent bonds (such as imines, disulfides, and metal coordination bonds). The design strategies, responsiveness, and application potential of key carrier materials are evaluated. In addition, the applications of pH-responsive release technologies in nutrient delivery, flavor encapsulation, and food preservation are highlighted, demonstrating enhanced bioavailability, extended shelf life, and improved sensory quality. Despite promising advancements achieved so far, significant challenges remain in ensuring material stability, and meeting safety and regulatory requirements. Future research directions are proposed, including the development of food-grade, eco-friendly, and stable carrier materials, the leveraging of AI-driven optimization for integrated systems, integrating multi-stimuli responsiveness, and establishing robust safety profiles to facilitate regulatory approval, collectively establishing a solid foundation for next-generation sustainable and intelligent food packaging and delivery systems.

Indexed as

controlled release mechanismsdesign strategiesfood preservationpH-responsivepolymer

Identifiers

PMID41300054
PMCPMC12651379

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.