Evidence map›Paper›PMID 41300437›Full record

ArticleAntioxidants (Basel, Switzerland)2025

Nrf2 Activated by PD-MSCs Attenuates Oxidative Stress in a Hydrogen Peroxide-Injured Retinal Pigment Epithelial Cell Line.

Se Jin Hong, Dae-Hyun Lee, Jeong Woo Choi, Hankyu Lee, Youngje Sung, Gi Jin Kim

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Se Jin HongDivision of Life Sciences, Department of Life Science, Graduate School, CHA University, Seongnam-si 13488, Republic of Korea.ORCID 0009-0004-0008-9268
Dae-Hyun LeeDivision of Life Sciences, Department of Life Science, Graduate School, CHA University, Seongnam-si 13488, Republic of Korea.ORCID 0000-0002-3856-5029
Jeong Woo ChoiDepartment of Biomedical Science, CHA University, Pocheon-si 11160, Republic of Korea.
Hankyu LeeDepartment of Biomedical Science, CHA University, Pocheon-si 11160, Republic of Korea.
Youngje SungDepartment of Ophthalmology CHA Bundang Medical Center, CHA University, Seongnam-si 13488, Republic of Korea.ORCID 0000-0002-2140-275X
Gi Jin KimDivision of Life Sciences, Department of Life Science, Graduate School, CHA University, Seongnam-si 13488, Republic of Korea.ORCID 0000-0002-2320-7157

Funding

Industry - Academia - Research Institute (IAR) Collabo R&D Fund Grant funded by the Korean Government RS - 2025 - 431 02313877
6 · The paper itself

Abstract

Age-related macular degeneration (AMD) is a retinal degenerative disease caused by oxidative stress. Thus, we aimed to reduce oxidative stress through the use of placenta-derived mesenchymal stem cells (PD-MSCs). To induce oxidative stress in ARPE-19 cells, we treated them with 200 µM hydrogen peroxide (H

Indexed as

age-related macular degenerationARPE-19KEAP1mitochondrial dynamicsNrf2oxidative stressplacenta-derived mesenchymal stem cells

Identifiers

PMID41300437
PMCPMC12649114

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.