Evidence mapPaperPMID 41300495Full record

ArticleAntioxidants (Basel, Switzerland)2025

New Insights into Potential Anti-Aging and Fatigue Effects of a Dietary Supplement from the Resveratrol Beverage in Aged SAMP8 Mice.

Yu-Chien Chen, Ming-Yu Chou, Po-Hsien Li, Ying-Shen Lin, Mei-Due Yang, Ching-Hsin Chi, Ping-Hsiu Huang, Yun-Jhen Wei, Ming-Fu Wang, Chun-Yen Kuo

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yu-Chien ChenDepartment of Food and Nutrition, Providence University, Taichung 433303, Taiwan.
Ming-Yu ChouInternational Aging Industry Research & Development Center (AIC), Providence University, Taichung 433303, Taiwan.
Po-Hsien LiDepartment of Food and Nutrition, Providence University, Taichung 433303, Taiwan.ORCID 0000-0001-9686-8434
Ying-Shen LinPh.D. Program in Health and Social Welfare for Indigenous Peoples, Providence University, Taichung 433303, Taiwan.
Mei-Due YangDepartment of Surgery Department of Clinical Nutrition, China Medical University Hospital, Taichung 40201, Taiwan.
Ching-Hsin ChiInternational Aging Industry Research & Development Center (AIC), Providence University, Taichung 433303, Taiwan.
Ping-Hsiu HuangDepartment of Food Science, National Chiayi University, Chiayi City 600355, Taiwan.
Yun-Jhen WeiDepartment of Food and Nutrition, Providence University, Taichung 433303, Taiwan.
Ming-Fu WangDepartment of Food and Nutrition, Providence University, Taichung 433303, Taiwan.
Chun-Yen KuoPh.D. Program in Health and Social Welfare for Indigenous Peoples, Providence University, Taichung 433303, Taiwan.

Funding

Healthtake Corporation Not applicableShan Ben Fu Ye International Co., LTD Not applicable
6 · The paper itself

Abstract

This study investigated the anti-fatigue and anti-aging benefits of continuous intake of resveratrol (RES)-rich beverages. Locomotion and forelimb grip strength performance were significantly improved in medium- and high-dose RES groups. In terms of aging indices, the scores for the medium- and high-dose groups were significantly lower than those of the control group. In the PAT and active shuttle avoidance tests, the three RES groups performed better than the control group. A significant increase in SOD and catalase activity in the liver and a reduction in TBARS and 8-OHdG levels in the brain were observed in the medium- and high-dose groups. Thus, supplementation with RES-rich beverages for 13 weeks significantly improved fatigue, locomotor performance, learning and memory abilities, and liver antioxidant activity and reduced brain peroxide levels in SAMP8 mice.

Indexed as

active shuttle avoidance testsglycogenpassive avoidance taskresveratrol

Identifiers

PMID41300495
PMCPMC12649198

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.