Evidence map›Paper›PMID 41300770›Full record

ReviewGenes2025

Sex-Specific Molecular and Genomic Responses to Endocrine Disruptors in Aquatic Species: The Central Role of Vitellogenin.

Faustina Barbara Cannea, Cristina Porcu, Maria Cristina Follesa, Alessandra Padiglia

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Faustina Barbara CanneaDepartment of Life and Environmental Sciences (DiSVA), Biomedical Section, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, 09042 Cagliari, Italy.
Cristina PorcuDepartment of Life and Environmental Sciences (DiSVA), Marine Bioecology Section, University of Cagliari, Via T. Fiorelli 1, 09126 Cagliari, Italy.
Maria Cristina FollesaDepartment of Life and Environmental Sciences (DiSVA), Marine Bioecology Section, University of Cagliari, Via T. Fiorelli 1, 09126 Cagliari, Italy.
Alessandra PadigliaDepartment of Life and Environmental Sciences (DiSVA), Biomedical Section, University of Cagliari, Cittadella Universitaria di Monserrato, Monserrato, 09042 Cagliari, Italy.ORCID 0000-0002-0540-3082

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocrine-disrupting chemicals (EDCs) are widespread contaminants that interfere with hormonal signaling and compromise reproductive success in aquatic organisms. Vitellogenin (VTG) is one of the most widely established biomarkers of estrogenic exposure, especially in males and juveniles. However, evidence from multi-omics studies indicates that VTG induction occurs within broader transcriptional and regulatory networks, involving genes such as

Indexed as

Aquatic OrganismsEndocrine DisruptorsVitellogeninsAnimalsEpigenesis, GeneticFemaleGenomicsMaleReproductionEndocrine DisruptorsVitellogeninsadverse outcome pathwayaquatic organismsbiomarkersecogenomicsendocrine-disrupting chemicalsepigenetic regulationomics-based integrationsex-specific gene expressiontranscriptomicsvitellogenin

Identifiers

PMID41300770
PMCPMC12652119

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.