Evidence mapPaperPMID 41300829Full record

SynthesisGenes2025

Genetic Assessment and Clinical Correlates in Severe Hypertriglyceridemia: A Systematic Review.

Carmine De Luca, Paola Ciciola, Guido D'Errico, Maria Donata Di Taranto, Giuliana Fortunato, Carina Gross, Jonathan Garn, Gabriella Iannuzzo, Matteo Di Minno, Ilenia Calcaterra

Abstract readSystematic Review
In one paragraph

Synthesis in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Genetic Determinants of Severe Hypertriglyceridemia: Rare Variants inInternational journal of molecular sciences · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carmine De LucaDepartment of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy.ORCID 0009-0004-6875-9133
Paola CiciolaDepartment of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy.
Guido D'ErricoDepartment of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy.
Maria Donata Di TarantoDepartment of Molecular Medicine and Medical Biotechnologies, CEINGE Advanced Biotechnologies S.C. A R.L, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-0618-7940
Giuliana FortunatoDepartment of Molecular Medicine and Medical Biotechnologies, CEINGE Advanced Biotechnologies S.C. A R.L, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-2209-383X
Carina GrossFaculty of Medicine, Hannover Medical School (MHH), 30625 Hannover, Germany.
Jonathan GarnFaculty of Medicine, Hannover Medical School (MHH), 30625 Hannover, Germany.
Gabriella IannuzzoDepartment of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-7392-5544
Matteo Di MinnoDepartment of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0001-8059-3819
Ilenia CalcaterraDepartment of Clinical Medicine and Surgery, University of Naples Federico II, 80131 Naples, Italy.

Funding

Ministero dell'Istruzione e del Merito NextGenerationEU. Project code - CUP u.o. - NRRP M6C2I2.1 NextGenerationEU; PNRR-MAD-2022-12375721; CUP: C63C22001520006
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hyperlipoproteinemia Type IHypertriglyceridemiaAngiopoietin-Like Protein 3Apolipoprotein C-IIApolipoprotein C-IIIHumansLipoprotein LipaseMembrane ProteinsPancreatitisReceptors, LipoproteinTriglyceridesAngiopoietin-Like Protein 3ANGPTL3 protein, humanApolipoprotein C-IIApolipoprotein C-IIIGPIHBP1 protein, humanLipoprotein LipaseLMF1 protein, humanLPL protein, humanMembrane ProteinsReceptors, LipoproteinTriglyceridesfamilial chylomicronemia syndrome (FCS)metabolic dysfunction-associated steatotic liver disease (MASLD)polygenic hypertriglyceridemiaprecision medicinesevere hypertriglyceridemia

Identifiers

PMID41300829
PMCPMC12652249

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.