Evidence map›Paper›PMID 41301120›Full record

ArticleBioengineering (Basel, Switzerland)2025

LIPUS Enhances Gallbladder Motility via ANO1 in Acute Cholecystitis Guinea Pigs.

Liping Liu, Xinhai Mo, Run Guo, Fang Chen, Fan Ding, Gang Zhao, Bo Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liping LiuDepartment of Ultrasound in Medicine, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200120, China.
Xinhai MoDepartment of Ultrasound in Medicine, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200120, China.
Run GuoDepartment of Ultrasound in Medicine, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200120, China.
Fang ChenDepartment of Ultrasound in Medicine, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200120, China.ORCID 0000-0002-1470-7942
Fan DingDepartment of Ultrasound in Medicine, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200120, China.ORCID 0000-0002-4624-3134
Gang ZhaoCenter of Gallbladder Disease, Shanghai East Hospital, Institution of Gallstone Disease, School of Medicine, Tongji University, Shanghai 200123, China.
Bo ZhangDepartment of Ultrasound in Medicine, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200120, China.

Funding

China Postdoctoral Science Foundation 2023M732652Important Weak Subject Construction Project of Shanghai Pudong New Area Health Commission PWZbr2022-12Shanghai Post-doctoral Excellence Program 2022561Youth Cultivation Program of Shanghai East Hospital DFPY2022007
6 · The paper itself

Abstract

backgroundAcute cholecystitis (AC) is characterized by gallbladder inflammation and is commonly accompanied by disordered gallbladder motility. Although laparoscopic cholecystectomy is the standard treatment, it carries procedure-related risks. Low-intensity pulsed ultrasound (LIPUS), a safe and noninvasive modality widely applied for muscle repair, may offer therapeutic benefits for AC-associated motility dysfunction.

methodsIn vivo, LIPUS (0.5 W/cm

resultsLIPUS increased intracellular Ca

conclusionsLIPUS alleviates gallbladder contractile dysfunction in acute cholecystitis by acting on ICCs through mechanisms involving the promotion of ICC recovery and a reduction in inflammation.

Indexed as

acute cholecystitiscalcium signalinggallbladder motilityinflammationinterstitial cells of Cajallow-intensity pulsed ultrasound

Identifiers

PMID41301120
PMCPMC12649647

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.