ReviewBioengineering (Basel, Switzerland)2025
The Impact of Small Incision Lenticule Extraction on the Biomechanical Properties of the Cornea: A Review.
Review in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, due to advancements in keratorefractive surgery, small incision lenticule extraction (SMILE) has become increasingly recognized as a top surgical technique for treating refractive defects. The technology employs a femtosecond laser to precisely incise a stromal lenticule, which is subsequently extracted through a small incision, thereby preserving the front and most rigid regions of the cornea with minimal damage. Despite the widespread recognition of SMILE for its safety, biomechanical stability, effectiveness, and predictability, studies consistently document occurrences of postoperative keratectasia and a notable reduction in corneal biomechanical stability following the surgery. Hence, it is imperative to conduct further research on the several parameters linked to corneal biomechanical stability following SMILE. This narrative review comprehensively synthesizes the current literature on this topic and examines the literature on the evaluation of corneal biomechanics before and after SMILE. It provides a thorough review of the fundamental principles of corneal biomechanics, measurement techniques, the impact of various keratorefractive surgeries on corneal biomechanics, and the mechanisms through which SMILE affects corneal biomechanics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.