Evidence map›Paper›PMID 41301278›Full record

ReviewBehavioral sciences (Basel, Switzerland)2025

Systematic Review and Meta-Analysis of Explainable Machine Learning Models for Clinical Depression Detection.

Ariosto Trelles, Tomás Fontaines Ruiz, Antonio Ponce Rojo

Abstract readReview
In one paragraph

Review in Behavioral sciences (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ariosto TrellesMaster's Program in Clinical Psychology, Specialization in Psychotherapy, Universidad Técnica de Machala, Machala 070205, Ecuador.ORCID 0009-0007-4259-6198
Tomás Fontaines RuizFaculty of Business Sciences, Accounting and Auditing Program, Universidad Técnica de Machala, Machala 070205, Ecuador.ORCID 0000-0002-2372-1850
Antonio Ponce RojoCentro Universitario de Los Altos, Universidad de Guadalajara, Guadalajara 44160, Mexico.ORCID 0000-0002-8406-0435

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is among the most prevalent mental disorders, and its early detection is essential to improving therapeutic outcomes in psychotherapy. This systematic review and meta-analysis evaluated the accuracy, interpretability, and generalizability of supervised algorithms (SVM, Random Forest, XGBoost, and GCN) for clinical detection of depression using real-world data. Following PRISMA guidelines, 20 studies published between 2014 and 2025 were analyzed across major scientific databases. Extracted metrics included F1-Score, AUC-ROC, interpretability methods (SHAP/LIME), and cross-validation strategies, with statistical analyses using ANOVA and Pearson correlations. Results showed that XGBoost achieved the best average performance (F1-Score: 0.86; AUC-ROC: 0.84), although differences across algorithms were not statistically significant (

Indexed as

depressionexplainabilitymachine learning

Identifiers

PMID41301278
PMCPMC12649417

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.