ArticleBiomolecules2025
Decreased PPM1B Expression Drives PRMT5-Mediated Histone Modification in Lung Cancer Progression.
Attila Makai, Ilka Keller, Fanni A Szalmás, Ádám Ungvári, Dániel Horváth, Evelin Major, Attila Enyedi, István Takács, Beáta Lontay
Abstract read
In one paragraphArticle in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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5 · Who and what moneyAuthors and funding
9 authors.
Attila MakaiHealth Care Service Units, Pulmonology Clinic, University of Debrecen Clinical Center, University of Debrecen, H-4032 Debrecen, Hungary.
Ilka KellerDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0009-0008-4300-0808 Fanni A SzalmásDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Ádám UngváriDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Dániel HorváthDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Evelin MajorDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Attila EnyediHealth Care Service Units, Department of Surgery, University of Debrecen Clinical Center, University of Debrecen, H-4032 Debrecen, Hungary.
István TakácsHealth Care Service Units, Department of Surgery, University of Debrecen Clinical Center, University of Debrecen, H-4032 Debrecen, Hungary.
Beáta LontayDepartment of Medical Chemistry, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-2545-8275 Funding
National Research, Development and Innovation Office FK125043National Research, Development and Innovation Office K143533University of Debrecen 1G3DBKJ0BFTK 247
6 · The paper itselfAbstract
Pulmonary carcinoma remains a highly aggressive malignancy driven by complex signaling and epigenetic dysregulation. This study investigates a novel oncogenic pathway involving the Mg
Indexed as
Histone CodeHistonesLung NeoplasmsProtein-Arginine N-MethyltransferasesProtein Phosphatase 2CAdenocarcinoma of LungCarcinoma, Squamous CellCell Line, TumorDisease ProgressionGene Expression Regulation, NeoplasticHumansPhosphorylationHistonesPPM1B protein, humanPRMT5 protein, humanProtein-Arginine N-MethyltransferasesProtein Phosphatase 2Cadenocarcinomalung cancermethylationplanocellular carcinomaprotein arginine methyltransferase 5protein phosphatases
Identifiers
PMID41301499
PMCPMC12649863
What Socratic holds
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