Evidence mapPaperPMID 41301531Full record

ReviewBiomolecules2025

Antimicrobial Peptides for Skin Wound Healing.

Yifan Wu, Tingting Liu, Lili Jin, Chuyuan Wang, Dianbao Zhang

Abstract readReview
In one paragraph

Review in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
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  5. Article
  6. Review
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  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yifan WuDepartment of Stem Cells and Regenerative Medicine, China Medical University, Shenyang 110122, China.
Tingting LiuDepartment of Pharmacy, Liaoning Agricultural Technical College, Yingkou 115009, China.
Lili JinSchool of Life Sciences, Liaoning University, Shenyang 110036, China.
Chuyuan WangDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of China Medical University, Shenyang 110001, China.
Dianbao ZhangDepartment of Stem Cells and Regenerative Medicine, China Medical University, Shenyang 110122, China.ORCID 0000-0001-7063-7742

Funding

Basic Research Foundation of the Educational Department of Liaoning Province JYTZD2023100Key Research Foundation of the Educational Department of Liaoning Province LJKZZ20220017National Natural Science Foundation of China 32171532National Natural Science Foundation of China 82473510Natural Science Foundation of Liaoning Province 2023JH2/20200141Natural Science Foundation of Liaoning Province 2023-MSLH-304
6 · The paper itself

Abstract

Skin wound healing is a highly regulated biological process that requires the coordinated activity of multiple cell types. However, this process can be significantly impaired by factors such as metabolic diseases and infections, posing ongoing challenges for current treatment strategies. As a critical defense mechanism for cells and organisms against external threats, antimicrobial peptides (AMPs) hold great potential to enhance both the rate and quality of healing in both acute and chronic wounds. AMPs play a crucial role in promoting skin wound healing through mechanisms such as keratinocyte migration and proliferation, collagen synthesis and tissue remodeling, promotion of angiogenesis, immunomodulatory effects and broad-spectrum antimicrobial activity. Moreover, structural modifications and optimized delivery systems have further enhanced the stability and efficacy of AMPs. This paper explores the mechanisms by which AMPs aid in the healing of damaged skin and reviews the types of AMPs in clinical trials, providing a foundation for their development and clinical application.

Indexed as

Antimicrobial PeptidesSkinWound HealingAnimalsHumansAntimicrobial Peptidesangiogenesisantimicrobial peptides (AMPs)collagen synthesiskeratinocyteswound healing

Identifiers

PMID41301531
PMCPMC12650420

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.