Evidence map›Paper›PMID 41301694›Full record

ReviewBiomedicines2025

Advanced Neuroimaging and Emerging Systemic Therapies in Glioblastoma: Current Evidence and Future Directions.

Ilona Bar-Letkiewicz, Anna Pieczyńska, Małgorzata Dudzic, Michał Szkudlarek, Krystyna Adamska, Katarzyna Hojan

Abstract readReview
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ilona Bar-LetkiewiczGreater Poland Cancer Centre, 15 Garbary St., 61-866 Poznan, Poland.ORCID 0000-0003-4654-3214
Anna PieczyńskaGreater Poland Cancer Centre, 15 Garbary St., 61-866 Poznan, Poland.ORCID 0000-0002-0349-7118
Małgorzata DudzicJoseph Strus Municipal Hospital in Poznan, Department of Neurology, 3 Szwajcarska St., 61-285 Poznan, Poland.ORCID 0009-0006-4388-9390
Michał SzkudlarekDepartment of Ecology and Anthropology, Institute of Biology, University of Szczecin, 13 Wąska St., 71-415 Szczecin, Poland.ORCID 0000-0003-2655-3140
Krystyna AdamskaGreater Poland Cancer Centre, 15 Garbary St., 61-866 Poznan, Poland.
Katarzyna HojanGreater Poland Cancer Centre, 15 Garbary St., 61-866 Poznan, Poland.ORCID 0000-0002-6166-9424

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite technological progress, glioblastoma (GBM) continues to confer dismal prognoses. Modern neuroimaging methods are assuming an ever greater role in diagnosing and monitoring brain tumors. This review shows current neuroimaging approaches and systemic therapeutic strategies for glioblastoma, with a focus on emerging and innovative treatments. Advances in multiparametric magnetic resonance imaging-MRI (diffusion, perfusion, and spectroscopy) and novel positron emission tomography (PET) tracers, complemented by radiomics and artificial intelligence (AI), now refine tumor delineation, differentiate progression from treatment effects, and may help predict treatment responses. Maximal safe resection followed by chemoradiotherapy with temozolomide remains the standard, with the greatest benefit seen in O

Indexed as

artificial intelligenceCAR-T cellsglioblastomaMGMT promoter methylationmultiparametric MRIPET tracersradiomicstargeted therapytemozolomide

Identifiers

PMID41301694
PMCPMC12650646

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.