Evidence map›Paper›PMID 41301724›Full record

ArticleBiomedicines2025

Artificial Intelligence-Guided Molecular Determinants of PI3K Pathway Alterations in Early-Onset Colorectal Cancer Among High-Risk Groups Receiving FOLFOX.

Fernando C Diaz, Brigette Waldrup, Francisco G Carranza, Sophia Manjarrez, Enrique Velazquez-Villarreal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fernando C DiazLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27514, USA.
Brigette WaldrupDepartment of Integrative Translational Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.ORCID 0009-0009-5991-9779
Francisco G CarranzaDepartment of Integrative Translational Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.ORCID 0000-0003-1789-4197
Sophia ManjarrezDepartment of Integrative Translational Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.
Enrique Velazquez-VillarrealDepartment of Integrative Translational Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.ORCID 0000-0002-3603-6414

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI Victoria L. Seewaldt · 1985 to 2026
$86.3M
USC PE-GCS: Optimizing Engagement of Hispanic Colorectal Cancer Patients in Cancer Genomic Characterization StudiesU2CCA252971 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JOHN D. CARPTEN, HEINZ JOSEF LENZ · 2021 to 2026
$19.3M
Project 2U54CA285116 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI ERNEST MARTINEZ, Victoria L. Seewaldt · 2023 to 2026
$6.8M
Research EducationU54CA285114 · NCI · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI DAVID D LO · 2023 to 2026
$6.2M
NCI NIH HHS P30CA033572NCI NIH HHS U2CCA252971NCI NIH HHS U54 CA285114NCI NIH HHS U54 CA285116NCI NIH HHS U54CA285116
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

artificial intelligencecancer disparitiescolorectal cancerearly-onset colorectal cancer (EOCRC)FOLFOXgenomicsLLMPI3K pathwayprecision oncologytherapeutic

Identifiers

PMID41301724
PMCPMC12650178

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.