Evidence map›Paper›PMID 41301973›Full record

ArticleAnimals : an open access journal from MDPI2025

Study on the Development and Formation Specifics of Longissimus Dorsi Muscles in Ziwuling Black Goats.

Hailong Guo, Fuyue Shi, Lingrong Gu, Yanyan Wang, Yangyang Yue, Wei Huang, Yongqiang Yang, Panlong Sun, Wenyong Xue, Xiaoqiang Zhang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hailong GuoAnimal Husbandry and Veterinary Research Institute of Gansu Province, Pingliang 744000, China.
Fuyue ShiAnimal Husbandry and Veterinary Research Institute of Gansu Province, Pingliang 744000, China.
Lingrong GuAnimal Husbandry and Veterinary Research Institute of Gansu Province, Pingliang 744000, China.
Yanyan WangAnimal Husbandry and Veterinary Research Institute of Gansu Province, Pingliang 744000, China.
Yangyang YueAnimal Husbandry and Veterinary Research Institute of Gansu Province, Pingliang 744000, China.
Wei HuangGansu Key Laboratory of Herbivorous Animal Science, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Yongqiang YangJingning County Animal Husbandry and Veterinary Center, Pingliang 743400, China.
Panlong SunZhuanglang County Animal Husbandry and Veterinary Center, Pingliang 744600, China.
Wenyong XueHuating City Animal Husbandry Science and Technology Development Service Center, Huating 744100, China.
Xiaoqiang ZhangJingchuan County Animal Husbandry and Veterinary Center, Pingliang 744300, China.
Xiaomei ZhuChongxin County Animal Husbandry and Veterinary Center, Pingliang 744200, China.
Pengyang ShaoGansu Key Laboratory of Herbivorous Animal Science, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.ORCID 0009-0009-5348-6781
Yapeng HeGansu Key Laboratory of Herbivorous Animal Science, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Jianfeng XuAnimal Husbandry and Veterinary Research Institute of Gansu Province, Pingliang 744000, China.
Xiu LiuGansu Key Laboratory of Herbivorous Animal Science, College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.ORCID 0000-0001-6057-2551

Funding

Jianfeng Xu 24ZYQL003Pengyang Shao 2026CXZX-819Xiu Liu 2025CYZC-043Yapeng He 2026CXZX-823
6 · The paper itself

Abstract

To clarify the relationship between muscle development and meat quality in Ziwuling black goats, this study used the longissimus dorsi muscle of 6-month-old and 12-month-old goats as samples. With HE staining, fast-slow myofiber immunofluorescence double staining, and transcriptome sequencing, this study analyzed muscle structure, myofiber type transformation, and molecular regulation. Results showed that 6-month-olds had higher myofiber density and smaller diameter; 12-month-olds showed myofiber hypertrophy (larger diameter); immunofluorescence revealed more fast-twitch myofibers (Type II) at 6 months and increased slow-twitch ones (Type I) at 12 months. Transcriptome sequencing identified 387 differentially expressed genes (DEGs: 156 upregulated, 231 downregulated). GO analysis indicated that DEGs are involved in skeletal muscle growth, cAMP biosynthesis, etc.; KEGG analysis showed enrichment in arginine-proline metabolism and AMPK/MAPK signaling pathways (AMPK regulates fatty acid metabolism genes like

Indexed as

different ageslongissimus dorsi musclemorphologytranscriptomicsZiwuling black goats

Identifiers

PMID41301973
PMCPMC12649415

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.