Evidence map›Paper›PMID 41301990›Full record

ArticleAnimals : an open access journal from MDPI2025

GWAS Reveals Key Candidate Genes Associated with Milk-Production in Saanen Goats.

Fu Li, Yonglong He, Hanbing Yan, Jiaqi Bu, Zhanhang Wang, Xiaolong Xu, Danni Li, Binyun Cao, Xiaopeng An

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fu LiCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.ORCID 0000-0001-9087-9212
Yonglong HeCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Hanbing YanCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Jiaqi BuCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Zhanhang WangCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Xiaolong XuCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Danni LiCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Binyun CaoCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
Xiaopeng AnCollege of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.

Funding

the Key Research and Development Program of Shaanxi Province 2024NC-ZDCYL-03-01, 2024NC-YBXM-082, 2024NC-GJHX-22the Project of 'Development and Application of Milk Goat Genomic Liquid Chip' QY-HS-2024A-01the Special Fund for Guided Local Science and Technology Development by Shaanxi Provincial Central Government 2024ZY-CGZY-20, 2024ZY-CGZY-22
6 · The paper itself

Abstract

Milk-production is one of the most important economic traits in dairy goats. Fundamentally, increasing milk-production at the genetic level can provide potential genetic markers for improving milk-production in dairy goats. Previous studies have shown that milk-production traits in dairy goats are highly polygenic and can be influenced by multiple genes. We therefore performed high-throughput sequencing on 350 Saanen dairy goats and conducted a genome-wide association study (GWAS) on the sequencing and production data. A total of 9,667,930 valid SNPs were identified, among which approximately 51% of the mutations were synonymous changes, and apart from unknown mutations, only a few changes affected gene expression. Finally, 318 SNP loci and 244 candidate genes were selected. We selected 10 loci most likely to influence these traits for large-scale population-based identification. Finally, four candidate genes,

Indexed as

candidate genesdairy goatGWASmilk-productionSNP

Identifiers

PMID41301990
PMCPMC12649104

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.