Evidence map›Paper›PMID 41302180›Full record

ArticleLife (Basel, Switzerland)2025

Guiding Antibiotic Therapy with Machine Learning: Real-World Applications of a CDSS in Bacteremia Management.

Juan Carlos Gómez de la Torre, Ari Frenkel, Carlos Chavez-Lencinas, Alicia Rendon, Yoshie Higuchi, Jose M Vela-Ruiz, Jacob Calpey, Ryan Beaton, Isaac Elijah, Inbal Shachar and 7 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Juan Carlos Gómez de la TorreClinical Laboratory Roe, Lima 15076, Peru.ORCID 0000-0003-4566-2027
Ari FrenkelArkstone Medical Solutions, Boca Raton, FL 33428, USA.ORCID 0009-0002-3194-8614
Carlos Chavez-LencinasHospital Nacional Edgardo Rebagliati Martins, Lima 15073, Peru.ORCID 0000-0002-9584-039X
Alicia RendonArkstone Medical Solutions, Boca Raton, FL 33428, USA.
Yoshie HiguchiClinical Laboratory Roe, Lima 15076, Peru.
Jose M Vela-RuizFaculty of Medicine, Ricardo Palma University, Lima 15039, Peru.ORCID 0000-0003-1811-4682
Jacob CalpeyDepartment of Medicine, FAU Charles E. Schmidt College of Medicine, Boca Raton, FL 33431, USA.ORCID 0009-0008-5079-989X
Ryan BeatonDepartment of Medicine, FAU Charles E. Schmidt College of Medicine, Boca Raton, FL 33431, USA.ORCID 0009-0001-7816-0931
Isaac ElijahDepartment of Medicine, FAU Charles E. Schmidt College of Medicine, Boca Raton, FL 33431, USA.ORCID 0009-0001-8054-5670
Inbal ShacharDepartment of Medicine, FAU Charles E. Schmidt College of Medicine, Boca Raton, FL 33431, USA.
Everett KimDepartment of Medicine, FAU Charles E. Schmidt College of Medicine, Boca Raton, FL 33431, USA.
Sofia Valencia OsorioDepartment of Medicine, FAU Charles E. Schmidt College of Medicine, Boca Raton, FL 33431, USA.
Jason James LeeDepartment of Medicine, FAU Charles E. Schmidt College of Medicine, Boca Raton, FL 33431, USA.
Gabrielle GroganCollege of Science & Mathematics, University of North Georgia, Oakwood, GA 30566, USA.
Jessica SiegelLake Erie College of Osteopathic Medicine, Bradenton, FL 34211, USA.
Stephanie AllmanArkstone Medical Solutions, Boca Raton, FL 33428, USA.
Miguel Hueda-ZavaletaDiagnóstico, Tratamiento e Investigación de Enfermedades Infecciosas y Tropicales, Universidad Privada de Tacna, Tacna 23003, Peru.ORCID 0000-0002-8049-7787

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteremia is a life-threatening condition contributing significantly to sepsis-related mortality worldwide. With delayed appropriate antibiotic therapy, mortality increases by 20% regardless of antimicrobial resistance. This study evaluated the perceived clinical utility of Artificial Intelligence (AI)-powered Clinical Decision Support Systems (CDSSs) (OneChoice and OneChoice Fusion) among specialist physicians managing bacteremia cases. A cross-sectional survey was conducted with 65 unique specialist physicians from multiple medical specialties who were presented with clinical vignettes describing patients with bacteremia and 90 corresponding AI-CDSS recommendations. Participants assessed the perceived helpfulness of AI decision-making, the impact of AI recommendations on their own clinical judgment, and the concordance between AI recommendations and their own clinical judgment, as well as the validity of changing therapy based on CDSS recommendations. The study encompassed a diverse range of bacterial pathogens, with

Indexed as

antimicrobial stewardshipartificial intelligencebacteremiaclinical decision support systemsmachine learning

Identifiers

PMID41302180
PMCPMC12653489

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.