Evidence map›Paper›PMID 41302489›Full record

ArticleMolecules (Basel, Switzerland)2025

Integrated Machine Learning and Structure-Based Virtual Screening Identifies Natural Product Targeting 50S Ribosome Inhibitory Activity Against

Jixing Liu, Henry H Y Tong, Hang Zheng, Miriam Iun Fan Lei, Shu Li

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jixing LiuCentre for Artificial Intelligence Driven Drug Discovery, Faculty of Applied Sciences, Macao Polytechnic University, Macao 999078, China.ORCID 0000-0002-5402-0221
Henry H Y TongCentre for Artificial Intelligence Driven Drug Discovery, Faculty of Applied Sciences, Macao Polytechnic University, Macao 999078, China.ORCID 0000-0003-2687-741X
Hang ZhengSchool of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China.ORCID 0000-0002-2825-0576
Miriam Iun Fan LeiFaculty of Health Sciences and Sports, Macao Polytechnic University, Macao 999078, China.ORCID 0000-0003-4668-034X
Shu LiCentre for Artificial Intelligence Driven Drug Discovery, Faculty of Applied Sciences, Macao Polytechnic University, Macao 999078, China.ORCID 0000-0002-4434-6172

Funding

Macao Polytechnic University Foundation RP/FCA 07/2022
6 · The paper itself

Abstract

Acne vulgaris is a prevalent inflammatory disease of the pilosebaceous unit in which

Indexed as

Anti-Bacterial AgentsBiological ProductsMachine LearningPropionibacteriaceaeRibosomesAcne VulgarisHumansMicrobial Sensitivity TestsMolecular Docking SimulationQuantitative Structure-Activity RelationshipRNA, Ribosomal, 23SAnti-Bacterial AgentsBiological ProductsRNA, Ribosomal, 23S50S ribosomal subunitacne vulgarisCutibacterium acnesdockingmachine learningnatural productstripterin

Identifiers

PMID41302489
PMCPMC12655229

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.