Evidence map›Paper›PMID 41302529›Full record

ArticleMolecules (Basel, Switzerland)2025

Development and Validation of an HPLC-DAD Method for the Quantitative Determination of Benzoyl Peroxide, Curcumin, Rosmarinic Acid, Resveratrol and Salicylic Acid in a Face Mask-In Vitro/Ex Vivo Permeability Study.

Sofia Almpani, Maria Mitsiou, Paraskevi Kyriaki Monou, Catherine K Markopoulou

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sofia AlmpaniLaboratory of Pharmaceutical Analysis, Department of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Maria MitsiouLaboratory of Pharmaceutical Analysis, Department of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Paraskevi Kyriaki MonouLaboratory of Pharmaceutical Technology, Department of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0001-9305-8081
Catherine K MarkopoulouLaboratory of Pharmaceutical Analysis, Department of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acne is a common skin condition that causes pimples, redness and inflammation. Benzoyl peroxide (BENZ), salicylic acid (SAL), curcumin (CUR), rosmarinic acid (ROS) and resveratrol (RESV) exhibit antimicrobial, anti-inflammatory and antioxidant properties and are recommended for its treatment. These five active pharmaceutical ingredients (APIs) were incorporated into a green clay, honey and gelatin face mask and determined by an HPLC-DAD (diode array) method. For the chromatographic separation of the analytes, a gradient mobile phase with two solvents mixtures: A, comprising H

Indexed as

Benzoyl PeroxideCinnamatesCurcuminDepsidesMasksResveratrolSalicylic AcidAnimalsChromatography, High Pressure LiquidHumansPermeabilityRatsReproducibility of ResultsRosmarinic AcidBenzoyl PeroxideCinnamatesCurcuminDepsidesResveratrolRosmarinic AcidSalicylic Acidanti-acne facial maskbenzoyl peroxidecurcuminexperimental designHPLC-DADin vitro/ex vivo permeability studyrosmarinic acid and resveratrolsalicylic acid

Identifiers

PMID41302529
PMCPMC12655397

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.