Evidence map›Paper›PMID 41302976›Full record

ArticleJournal of clinical medicine2025

Fixation Stability as a Surrogate for Reading Abilities in Age-Related Macular Degeneration: A Perspective.

Carolina Molin, Edoardo Midena, Enrica Convento, Giulia Midena, Elisabetta Pilotto

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carolina MolinDepartment of Neuroscience-Ophthalmology, University of Padova, 35128 Padova, Italy.
Edoardo MidenaDepartment of Neuroscience-Ophthalmology, University of Padova, 35128 Padova, Italy.ORCID 0000-0003-3132-6233
Enrica ConventoDepartment of Neuroscience-Ophthalmology, University of Padova, 35128 Padova, Italy.
Giulia MidenaIRCCS-Fondazione Bietti, 00198 Rome, Italy.ORCID 0000-0003-4712-6631
Elisabetta PilottoDepartment of Neuroscience-Ophthalmology, University of Padova, 35128 Padova, Italy.ORCID 0000-0001-6677-7697

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related macular degeneration (AMD) significantly impacts central vision, fixation site and stability and reading abilities. This work aims to analyze the relationship between retinal fixation parameters measured using microperimetry and reading performance in patients with AMD. We identified the role of fixation stability measurement in the evaluation of reading abilities and discussed its implications both in clinical practice and in clinical trials. Our analysis highlights the importance of retinal fixation assessment as a precise surrogate for evaluating reading ability outcomes in AMD patients and as new clinical endpoint to demonstrate the functional effects of present and emerging target therapies.

Indexed as

age-related macular degenerationmicroperimetryreading performancereading speedretinal fixation stability

Identifiers

PMID41302976
PMCPMC12653221

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.