Evidence map›Paper›PMID 41303328›Full record

ArticleInternational journal of molecular sciences2025

Validation of

Ariane Wiegand, Marion Friske, Susanne Edelmann, Annika Bender, Lea Fischer, Peter Zill, Gabriele Koller, Georgy Bakalkin, Wolfgang H Sommer, Anita C Hansson and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ariane WiegandMax Planck Institute of Psychiatry, 80804 Munich, Germany.
Marion FriskeInstitute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany.ORCID 0000-0002-3334-2555
Susanne EdelmannDepartment of Psychiatry and Psychotherapy, Tuebingen Center for Mental Health (TüCMH), University Hospital of Tuebingen, Eberhard Karls University of Tuebingen, 72076 Tuebingen, Germany.
Annika BenderDepartment of Psychiatry and Psychotherapy, Tuebingen Center for Mental Health (TüCMH), University Hospital of Tuebingen, Eberhard Karls University of Tuebingen, 72076 Tuebingen, Germany.
Lea FischerDepartment of Psychiatry and Psychotherapy, Tuebingen Center for Mental Health (TüCMH), University Hospital of Tuebingen, Eberhard Karls University of Tuebingen, 72076 Tuebingen, Germany.ORCID 0009-0005-6764-2766
Peter ZillDepartment of Psychiatry and Psychotherapy, University Hospital, Ludwig Maximilian University, 80336 Munich, Germany.
Gabriele KollerDepartment of Psychiatry and Psychotherapy, University Hospital, Ludwig Maximilian University, 80336 Munich, Germany.
Georgy BakalkinDepartment of Pharmaceutical Biosciences, Uppsala University, SE-752 37 Uppsala, Sweden.
Wolfgang H SommerInstitute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany.
Anita C HanssonInstitute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany.
Vanessa NieratschkerDepartment of Psychiatry and Psychotherapy, Tuebingen Center for Mental Health (TüCMH), University Hospital of Tuebingen, Eberhard Karls University of Tuebingen, 72076 Tuebingen, Germany.ORCID 0000-0001-7884-4500

Funding

Deutsche Forschungsgemeinschaft NI13332/13-1Deutsche Forschungsgemeinschaft TRR265German Federal Ministry of Education and Research (BMBF) 01ZX01909
6 · The paper itself

Abstract

Alcohol use disorder (AUD) is associated with widespread epigenetic alterations, including changes in DNA methylation (DNAm). This multi-cohort study validated and extended previous findings on DNAm of

Indexed as

AlcoholismBrainEpigenesis, GeneticNerve Tissue ProteinsUbiquitin-Protein LigasesAdultAnimalsBiomarkersCohort StudiesDNA MethylationFemaleHumansMaleMiddle AgedPrefrontal CortexRatsBiomarkersNerve Tissue ProteinsUbiquitin-Protein Ligasesalcohol use disorder (AUD)AUD animal modelDNA methylationepigeneticsGDAP1HECW2postmortem brainwhole blood

Identifiers

PMID41303328
PMCPMC12652996

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.