Evidence mapPaperPMID 41303475Full record

ReviewInternational journal of molecular sciences2025

Cardiac Involvement in Myotonic Dystrophy Type 1: Mechanisms, Clinical Perspectives, and Emerging Therapeutic Strategies.

Vamsi Krishna Murthy Ginjupalli, Jean-Baptiste Reisqs, Michael Cupelli, Mohamed Chahine, Mohamed Boutjdir

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vamsi Krishna Murthy GinjupalliCardiovascular Research Program, VA New York Harbor Healthcare System, New York, NY 11209, USA.ORCID 0000-0002-5022-1683
Jean-Baptiste ReisqsCardiovascular Research Program, VA New York Harbor Healthcare System, New York, NY 11209, USA.
Michael CupelliCardiovascular Research Program, VA New York Harbor Healthcare System, New York, NY 11209, USA.
Mohamed ChahineDepartment of Medicine, Faculty of Medicine, Université Laval, Quebec City, QC G1V 0A6, Canada.ORCID 0000-0002-9500-2839
Mohamed BoutjdirCardiovascular Research Program, VA New York Harbor Healthcare System, New York, NY 11209, USA.

Funding

CIHR MOP-111072CIHR MOP-130373Department of Defense W81XWH-21-1-0424Department of Defense W81XWH-21-1-0426NHLBI NIH HHS 1R01HL164415
6 · The paper itself

Abstract

Myotonic Dystrophy Type 1 (DM1) is a complex multisystemic genetic disorder caused by CTG repeat expansions in the

Indexed as

Heart DiseasesMyotonic DystrophyAnimalsGene EditingHumansMyotonin-Protein KinaseOligonucleotides, AntisenseRNA SplicingTrinucleotide Repeat ExpansionMyotonin-Protein KinaseOligonucleotides, Antisensearrhythmiascardiac conduction defectscardiac dysfunctioncardiac electrophysiologymyotonic dystrophy type 1preclinical modelstherapeutic pipeline

Identifiers

PMID41303475
PMCPMC12652575

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.