Evidence map›Paper›PMID 41303684›Full record

ArticleInternational journal of molecular sciences2025

The Mechanism of LTX

Jennifer K Blackburn, John-Paul Silva, Evelina Petitto, Dietmar Cholewa, Elizaveta Fasler-Kan, Kirill E Volynski, Yuri A Ushkaryov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jennifer K BlackburnMedway School of Pharmacy, University of Kent, Chatham ME4 4TB, UK.ORCID 0000-0002-2171-6716
John-Paul SilvaDepartment of Biological Sciences, Imperial College London, London SW7 2AZ, UK.ORCID 0000-0001-7239-8554
Evelina PetittoMedway School of Pharmacy, University of Kent, Chatham ME4 4TB, UK.ORCID 0000-0001-9814-9660
Dietmar CholewaDepartment of Pediatric Surgery, Inselspital Bern, University of Bern, CH-3010 Bern, Switzerland.ORCID 0000-0002-8100-0365
Elizaveta Fasler-KanDepartment of Pediatric Surgery, Inselspital Bern, University of Bern, CH-3010 Bern, Switzerland.ORCID 0000-0002-4466-2642
Kirill E VolynskiDepartment of Biological Sciences, Imperial College London, London SW7 2AZ, UK.ORCID 0000-0001-8208-1905
Yuri A UshkaryovMedway School of Pharmacy, University of Kent, Chatham ME4 4TB, UK.ORCID 0000-0002-5712-8297

Funding

Biotechnology and Biological Sciences Research Council 28/B14085Biotechnology and Biological Sciences Research Council BB/D523078/1Wellcome Trust GR074359
6 · The paper itself

Abstract

Store-operated Ca

Indexed as

CalciumCalcium Channels, N-TypeReceptors, G-Protein-CoupledReceptors, PeptideAnimalsCalcium SignalingCell Line, TumorMiceNeuronsSpider Venomsalpha-latrotoxinalpha-latrotoxin receptorCacna1b protein, mouseCalciumCalcium Channels, N-TypeReceptors, G-Protein-CoupledReceptors, PeptideSpider VenomsADGRL1Fluo-4fluorescent microscopyGCaMPlatrophilinLTXN4Cstore-operated calcium entryvoltage-gated calcium channels

Identifiers

PMID41303684
PMCPMC12653939

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.