Evidence map›Paper›PMID 41304169›Full record

ArticleMicroorganisms2025

Four-Year Longitudinal Epidemiological Study on the Association Between a Multi-Item Saliva Testing System and Oral and Gut Microbiota.

Satoshi Sato, Daisuke Chinda, Keita Mikami, Masakazu Tobinai, Nao Ishidoya, Keisuke Furusawa, Kaede Miyashiro, Kenta Yoshida, Chikara Iino, Kaori Sawada and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Satoshi SatoDepartment of Gastroenterology, Hematology, and Clinical Immunology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.ORCID 0000-0001-5569-7093
Daisuke ChindaDivision of Endoscopy, Hirosaki University Hospital, Hirosaki 036-8563, Japan.ORCID 0000-0003-1690-5923
Keita MikamiDepartment of Gastroenterology, Hematology, and Clinical Immunology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.
Masakazu TobinaiDepartment of Gastroenterology, Hematology, and Clinical Immunology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.
Nao IshidoyaDepartment of Gastroenterology, Hematology, and Clinical Immunology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.
Keisuke FurusawaDepartment of Gastroenterology, Hematology, and Clinical Immunology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.
Kaede MiyashiroDepartment of Gastroenterology, Hematology, and Clinical Immunology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.
Kenta YoshidaDepartment of Gastroenterology, Hematology, and Clinical Immunology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.ORCID 0000-0002-3897-5546
Chikara IinoDepartment of Gastroenterology, Hematology, and Clinical Immunology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.
Kaori SawadaDepartment of Preemptive Medicine, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.
Tatsuya MikamiDepartment of Preemptive Medicine, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.ORCID 0000-0002-6657-6446
Shigeyuki NakajiDepartment of Preemptive Medicine, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.ORCID 0000-0002-4190-5151
Koichi MurashitaResearch Institute of Health Innovation, Hirosaki University, Hirosaki 036-8562, Japan.
Hirotake SakurabaDepartment of Gastroenterology, Hematology, and Clinical Immunology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salivary Multi Test (SMT) is a device that can quickly and noninvasively measure seven parameters related to the oral environment using saliva as a sample: (1) bacteria that cause tooth decay, (2) acidity, (3) buffering capacity, (4) occult blood, (5) white blood cells, (6) protein, and (7) ammonia. This longitudinal study aimed to investigate the relationship between SMT and oral and gut microbiota in healthy general residents. After propensity score matching, 198 participants were included (low SMT group: 99 participants; high SMT group: 99 participants). We reclassified participants four years after the follow-up survey and compared the low- and high-SMT groups. The high SMT score group indicating a poor oral environment showed increased

Indexed as

gut microbiotamulti-item saliva testing systemOlsenellaoral microbiota

Identifiers

PMID41304169
PMCPMC12654230

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.