Evidence map›Paper›PMID 41304213›Full record

ArticleMicroorganisms2025

Norditerpene Natural Products from Subterranean Fungi with Anti-Parasitic Activity.

Alexandra Kolas, Yudi Rusman, Ana C R G Maia, Jessica M Williams, Jiashu Xie, Roshan Katekar, Fernanda G Fumuso, Alexis Cotto-Rosario, Chidiebere N Onoh, Hanen Baggar and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Tartrolon E rapidly blocks Toxoplasma gondii capacity to invade host cells.International journal for parasitology. Drugs and drug resistance · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Alexandra KolasDepartment of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN 55108, USA.
Yudi RusmanCenter for Drug Design, University of Minnesota, Minneapolis, MN 55455, USA.
Ana C R G MaiaDepartment of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0002-9455-2919
Jessica M WilliamsCenter for Drug Design, University of Minnesota, Minneapolis, MN 55455, USA.
Jiashu XieCenter for Drug Design, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-6148-5203
Roshan KatekarCenter for Drug Design, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0003-1374-0828
Fernanda G FumusoDepartment of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0002-4561-9005
Alexis Cotto-RosarioDepartment of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0003-0335-2207
Chidiebere N OnohDepartment of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN 55108, USA.
Hanen BaggarDepartment of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN 55108, USA.
Mary L PiaskowskiDepartment of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN 55108, USA.
Christian BaigorriaDivision of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, 12722 Research Parkway, Orlando, FL 32826, USA.
Raphaella PaesDivision of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, 12722 Research Parkway, Orlando, FL 32826, USA.ORCID 0000-0002-6146-5309
Debopam ChakrabartiDivision of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, 12722 Research Parkway, Orlando, FL 32826, USA.
Lyssa J WeibleCenter for Emerging and Reemerging Infectious Diseases (CERID), Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98109, USA.
Kayode K OjoCenter for Emerging and Reemerging Infectious Diseases (CERID), Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98109, USA.ORCID 0000-0002-2007-2170
Roberta M O'ConnorDepartment of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0003-2757-754X
Christine E SalomonCenter for Drug Design, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0003-4976-598X

Funding

Novel Antimalarials from FungiR01AI154777 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI CHAKRABARTI, DEBOPAM, CICHEWICZ, ROBERT HENRY · 2020 to 2024
$3.8M
Development of dual effective kinase inhibitors as syndromic treatment of Giardiasis and CryptosporidiosisR01AI179768 · NIAID · UNIVERSITY OF WASHINGTON · PI Erkang Fan, Kayode K Ojo · 2024 to 2026
$2.3M
Discovery of fungus-derived natural products as new and effective Antigiardial agents.R21AI182705 · NIAID · UNIVERSITY OF WASHINGTON · PI OJO, KAYODE K · 2024 to 2025
$461k
Antiparasitic metabolites from deep subterranean fungi for the treatment of cryptosporidiosis, an AIDS defining diseaseR21AI177019 · NIAID · UNIVERSITY OF MINNESOTA · PI O'CONNOR, ROBERTA M, SALOMON, CHRISTINE E · 2023 to 2024
$426k
NIAID NIH HHS R01 AI154777NIAID NIH HHS R01 AI179768NIAID NIH HHS R21 AI177019NIAID NIH HHS R21 AI182705NIH HHS 1R21AI177019-22
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anti-parasiticapicomplexaCryptosporidiumnatural productnorditerpeneoidiolactoneToxoplasma

Identifiers

PMID41304213
PMCPMC12654037

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.