Evidence map›Paper›PMID 41304276›Full record

ArticleMicroorganisms2025

The Nucleoid-Associated Protein Fis Represses Type 3 Fimbriae to Modulate Biofilm and Adherence Formation in

Santa Mejia-Ventura, Jorge Soria-Bustos, Fernando Chimal-Cázares, Gabriela Hernández-Martínez, Roberto Rosales-Reyes, Miguel A De la Cruz, Jorge A Yañez-Santos, Maria L Cedillo, Gonzalo Castillo-Rojas, Dimitris Georgellis and 1 more

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Santa Mejia-VenturaPosgrado en Ciencias Biológicas, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Jorge Soria-BustosCentro de Detección Biomolecular, Benemérita Universidad Autónoma de Puebla, Puebla 72592, Mexico.ORCID 0000-0002-1773-1657
Fernando Chimal-CázaresUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico.ORCID 0009-0002-9267-9702
Gabriela Hernández-MartínezUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico.
Roberto Rosales-ReyesUnidad de Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0001-9519-8766
Miguel A De la CruzCentro de Detección Biomolecular, Benemérita Universidad Autónoma de Puebla, Puebla 72592, Mexico.ORCID 0000-0001-6909-2941
Jorge A Yañez-SantosCentro de Detección Biomolecular, Benemérita Universidad Autónoma de Puebla, Puebla 72592, Mexico.
Maria L CedilloCentro de Detección Biomolecular, Benemérita Universidad Autónoma de Puebla, Puebla 72592, Mexico.
Gonzalo Castillo-RojasDepartamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Dimitris GeorgellisDepartamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.
Miguel A AresUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico.ORCID 0000-0003-2574-958X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nucleoid-associated protein Fis functions as a global regulator that influences various cellular processes in Gram-negative bacteria. In this study, we examined the role of Fis in the transcriptional regulation of type 3 fimbriae in

Indexed as

adherencebiofilmFisKlebsiella pneumoniaemrkAmrkHtype 3 fimbriae

Identifiers

PMID41304276
PMCPMC12655184

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.