Evidence map›Paper›PMID 41304669›Full record

ArticlePlants (Basel, Switzerland)2025

Searching for Hypoglycemic Compounds from Brazilian Medicinal Plants Through UPLC-HRMS and Molecular Docking.

Elisabeth Mariano Batista, Gabriela Araújo Freire, Caio Bruno Rodrigues Martins, Raimundo Rigoberto Barbosa Xavier Filho, Gisele Silvestre da Silva, Nylane Maria Nunes de Alencar, Paulo Riceli Vasconcelos Ribeiro, Natalia Florencio Martins, Yasmim Aquino Milhome, Helcio Silva Dos Santos and 3 more

Abstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Elisabeth Mariano BatistaPrograma de Pós-Graduação em Ciência e Tecnologia de Alimentos, Departamento de Engenharia de Alimentos, Universidade Federal do Ceará, Campus Pici, Fortaleza 60356-000, CE, Brazil.ORCID 0000-0001-5250-4110
Gabriela Araújo FreirePrograma de Pós-graduação em Farmacologia, Faculdade de Medicina, Departamento de Farmacologia e Fisiologia, Núcleo de Pesquisa e Desenvolvimento de Medicamentos (NPDM), Universidade Federal do Ceará, Fortaleza 60430-275, CE, Brazil.ORCID 0009-0001-4156-5222
Caio Bruno Rodrigues MartinsPrograma de Pós-graduação em Farmacologia, Faculdade de Medicina, Departamento de Farmacologia e Fisiologia, Núcleo de Pesquisa e Desenvolvimento de Medicamentos (NPDM), Universidade Federal do Ceará, Fortaleza 60430-275, CE, Brazil.ORCID 0000-0003-3837-3139
Raimundo Rigoberto Barbosa Xavier FilhoPrograma de Pós-Graduação em Ciências Naturais, Universidade Estadual do Ceará, Fortaleza 60714-903, CE, Brazil.ORCID 0000-0002-4078-1417
Gisele Silvestre da SilvaPrograma de Pós-graduação em Farmacologia, Faculdade de Medicina, Departamento de Farmacologia e Fisiologia, Núcleo de Pesquisa e Desenvolvimento de Medicamentos (NPDM), Universidade Federal do Ceará, Fortaleza 60430-275, CE, Brazil.ORCID 0000-0003-2771-5148
Nylane Maria Nunes de AlencarPrograma de Pós-graduação em Farmacologia, Faculdade de Medicina, Departamento de Farmacologia e Fisiologia, Núcleo de Pesquisa e Desenvolvimento de Medicamentos (NPDM), Universidade Federal do Ceará, Fortaleza 60430-275, CE, Brazil.ORCID 0000-0001-8340-4876
Paulo Riceli Vasconcelos RibeiroEmbrapa Agroindústria Tropical, Fortaleza 60020-181, CE, Brazil.ORCID 0000-0002-5258-4015
Natalia Florencio MartinsEmbrapa Agroindústria Tropical, Fortaleza 60020-181, CE, Brazil.ORCID 0000-0002-8816-4258
Yasmim Aquino MilhomeEmbrapa Agroindústria Tropical, Fortaleza 60020-181, CE, Brazil.ORCID 0000-0001-6561-8002
Helcio Silva Dos SantosPrograma de Pós-Graduação em Ciências Naturais, Universidade Estadual do Ceará, Fortaleza 60714-903, CE, Brazil.ORCID 0000-0001-5527-164X
Marisa Jadna Silva FredericoPrograma de Pós-graduação em Farmacologia, Faculdade de Medicina, Departamento de Farmacologia e Fisiologia, Núcleo de Pesquisa e Desenvolvimento de Medicamentos (NPDM), Universidade Federal do Ceará, Fortaleza 60430-275, CE, Brazil.ORCID 0000-0002-8254-4727
Luciana de Siqueira OliveiraPrograma de Pós-Graduação em Ciência e Tecnologia de Alimentos, Departamento de Engenharia de Alimentos, Universidade Federal do Ceará, Campus Pici, Fortaleza 60356-000, CE, Brazil.ORCID 0000-0003-3047-9211
Kirley Marques CanutoPrograma de Pós-Graduação em Ciências Naturais, Universidade Estadual do Ceará, Fortaleza 60714-903, CE, Brazil.ORCID 0000-0003-3194-6125

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88887.857033/2023-00National Council for Scientific and Technological Development 406690/ 2023-5
6 · The paper itself

Abstract

Type 2 diabetes mellitus remains a major global health challenge, and natural hypoglycemic compounds are of increasing interest. Aqueous extracts from five Brazilian medicinal plants (

Indexed as

Acanthaceaealpha-glucosidaseantidiabetic agentsdiabetesdisaccharidase inhibitionFabaceaeVerbenaceae

Identifiers

PMID41304669
PMCPMC12656556

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.