Evidence map›Paper›PMID 41304785›Full record

ArticlePharmaceutics2025

Novel Disulfiram-Loaded Metal-Organic Nanoparticles Inhibit Tumor Growth and Induce Immunogenic Cell Death of Triple-Negative Breast Cancer Cells.

Chung-Hui Huang, Xuejia Kang, Lang Zhou, Junwei Wang, Shuai Wu, Peizhen Sun, Qi Wang, Adam B Keeton, Pengyu Chen, Gary A Piazza

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chung-Hui HuangDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0003-0974-3532
Xuejia KangMaterials Engineering, Department of Mechanical Engineering, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0003-4336-2098
Lang ZhouMaterials Engineering, Department of Mechanical Engineering, Auburn University, Auburn, AL 36849, USA.
Junwei WangDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA.
Shuai WuMaterials Engineering, Department of Mechanical Engineering, Auburn University, Auburn, AL 36849, USA.ORCID 0009-0001-5599-9339
Peizhen SunMaterials Engineering, Department of Mechanical Engineering, Auburn University, Auburn, AL 36849, USA.
Qi WangDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA.
Adam B KeetonDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA.
Pengyu ChenMaterials Engineering, Department of Mechanical Engineering, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0003-3380-872X
Gary A PiazzaDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0003-4418-887X

Funding

Purchase of a modularized confocal microscopeR35GM133795 · NIGMS · AUBURN UNIVERSITY AT AUBURN · PI Pengyu Chen · 2019 to 2026
$3.3M
Novel inhibitor for oncogenic RAS for lung cancerR01CA254197 · NCI · AUBURN UNIVERSITY AT AUBURN · PI PIAZZA, GARY A · 2021 to 2025
$1.9M
National Institutes of Health (NIH) MIRA R35GM133795National Science Foundation (NSF) CAREER CBET-1943302NIGMS NIH HHS R35 GM133795NIH HHS R01CA254197
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

disulfiram-copper complex [Cu(DDC)2]immunogenic cell death (ICD)nanoparticle drug deliverytumor microenvironment modulation

Identifiers

PMID41304785
PMCPMC12655402

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.