ArticlePharmaceutics2025
Novel Disulfiram-Loaded Metal-Organic Nanoparticles Inhibit Tumor Growth and Induce Immunogenic Cell Death of Triple-Negative Breast Cancer Cells.
Chung-Hui Huang, Xuejia Kang, Lang Zhou, Junwei Wang, Shuai Wu, Peizhen Sun, Qi Wang, Adam B Keeton, Pengyu Chen, Gary A Piazza
Abstract read
In one paragraphArticle in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Chung-Hui HuangDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0003-0974-3532 Xuejia KangMaterials Engineering, Department of Mechanical Engineering, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0003-4336-2098 Lang ZhouMaterials Engineering, Department of Mechanical Engineering, Auburn University, Auburn, AL 36849, USA.
Junwei WangDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA.
Shuai WuMaterials Engineering, Department of Mechanical Engineering, Auburn University, Auburn, AL 36849, USA.ORCID 0009-0001-5599-9339 Peizhen SunMaterials Engineering, Department of Mechanical Engineering, Auburn University, Auburn, AL 36849, USA.
Qi WangDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA.
Adam B KeetonDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA.
Pengyu ChenMaterials Engineering, Department of Mechanical Engineering, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0003-3380-872X Gary A PiazzaDepartment of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0003-4418-887X Funding
Purchase of a modularized confocal microscopeR35GM133795 · NIGMS · AUBURN UNIVERSITY AT AUBURN · PI Pengyu Chen · 2019 to 2026
$3.3MNovel inhibitor for oncogenic RAS for lung cancerR01CA254197 · NCI · AUBURN UNIVERSITY AT AUBURN · PI PIAZZA, GARY A · 2021 to 2025
$1.9MNational Institutes of Health (NIH) MIRA R35GM133795National Science Foundation (NSF) CAREER CBET-1943302NIGMS NIH HHS R35 GM133795NIH HHS R01CA254197
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
disulfiram-copper complex [Cu(DDC)2]immunogenic cell death (ICD)nanoparticle drug deliverytumor microenvironment modulation
Identifiers
PMID41304785
PMCPMC12655402
What Socratic holds
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