Evidence map›Paper›PMID 41304839›Full record

ArticlePharmaceutics2025

Functional pH-Responsive Nanoparticles for Immune Reprogramming in MSS Colorectal Cancer via ER Stress-Induced Proteostasis Disruption, PD-L1-Targeting miRNA, and TLR7 Activation.

Yu-Li Lo, Hua-Ching Lin, Ching-Yao Li, Bryant Huang, Ching-Ping Yang, Hui-Yen Chuang, Tsui-Fen Chou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu-Li LoDepartment and Institute of Pharmacology, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0002-6548-3280
Hua-Ching LinDivision of Colorectal Surgery, Cheng-Hsin General Hospital, Taipei 112, Taiwan.ORCID 0000-0003-3958-3760
Ching-Yao LiDepartment and Institute of Pharmacology, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Bryant HuangDepartment and Institute of Pharmacology, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0009-0002-2683-8904
Ching-Ping YangDepartment and Institute of Pharmacology, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0002-4625-4140
Hui-Yen ChuangDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0003-4016-6753
Tsui-Fen ChouDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.ORCID 0000-0003-2410-2186

Funding

Higher Education Sprout Project of the National Yang Ming Chiao Tung University and Ministry of Education (MOE), Taiwan 114W020264National Science and Technology Council (NSTC) of Taiwan NSTC 114-2320-B-A49-012, NSTC 113-2320-B-A49-032, and MOST 110-2320-B-A49A-510-MY3the National Yang Ming Chiao Tung University and Cheng Hsin General Hospital(CY114-11) CY113-23 and CY114-11Veterans General Hospitals and University System of Taiwan VGHUST113-G2-2-3
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

colorectal cancerendoplasmic reticulum stressimmune checkpoint modulationsolid lipid nanoparticlestumor microenvironment

Identifiers

PMID41304839
PMCPMC12656422

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.