Evidence map›Paper›PMID 41304867›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

The SP1-SuperEnhancer-SPHK1 Axis Mediates Niraparib Resistance in TNBC.

Yu-Xia Yuan, Rui-Jia Chen, Gui-Hui Tu, Chao-Qi Li, Long-Long Xu, Yi-Ling Lu, Li-Xian Wu

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu-Xia YuanDepartment of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou 350000, China.
Rui-Jia ChenDepartment of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou 350000, China.ORCID 0000-0001-7076-619X
Gui-Hui TuDepartment of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou 350000, China.
Chao-Qi LiDepartment of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou 350000, China.ORCID 0009-0007-7339-8354
Long-Long XuDepartment of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou 350000, China.
Yi-Ling LuDepartment of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou 350000, China.
Li-Xian WuDepartment of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou 350000, China.ORCID 0000-0001-6505-0648

Funding

Natural Science Foundation of Fujian Province 2023J02016Startup Fund for Scientific Research of Fujian Medical University 2020QH2014
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

niraparibSP1sphingolipid metabolismSPHK1super-enhancers

Identifiers

PMID41304867
PMCPMC12655459

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.